(Q41925900)

14 October 2017

title

Beta-amyloid increases cathepsin D levels in hippocampus (English)

1 reference

14 October 2017

4

Lynch G

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14 October 2017

Hoffman KB

1

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14 October 2017

Bi X

series ordinal

2

1 reference

14 October 2017

Pham JT

series ordinal

3

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14 October 2017

language of work or name

English

0 references

publication date

1 July 1998

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14 October 2017

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14 October 2017

volume

250

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14 October 2017

issue

2

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14 October 2017

page(s)

75-78

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Induction of beta-amyloid-containing polypeptides in hippocampus: evidence for a concomitant loss of synaptic proteins and interactions with an excitotoxin

14 October 2017

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Stable maintenance of glutamate receptors and other synaptic components in long-term hippocampal slices

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Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein

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7 January 2021

Cytosolic proteolysis of tau by cathepsin D in hippocampus following suppression of cathepsins B and L.

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7 January 2021

Suppression of cathepsins B and L causes a proliferation of lysosomes and the formation of meganeurites in hippocampus.

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Ratio of pyramidal cells versus non-pyramidal cells in the human frontal isocortex and changes in ratio with ageing and Alzheimer's disease

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Preferential adsorption, internalization and resistance to degradation of the major isoform of the Alzheimer's amyloid peptide, A beta 1-42, in differentiated PC12 cells

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Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein

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Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain

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Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin.

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Colocalization of lysosomal hydrolase and beta-amyloid in diffuse plaques of the cerebellum and striatum in Alzheimer's disease and Down's syndrome

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Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

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Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

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7 January 2021

Amyloid beta-peptide is produced by cultured cells during normal metabolism

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Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain

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Anomalous accumulation of tau and ubiquitin immunoreactivities in rat brain caused by protease inhibition and by normal aging: a clue to PHF pathogenesis?

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7 January 2021

Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein

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7 January 2021

Increase in cathepsin D activity in rat brain in aging

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7 January 2021

Cathepsin D from Alzheimer's-Diseased and Normal Brains

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7 January 2021

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Comparative behaviour of calpain and cathepsin B toward peptidyl acyloxymethyl ketones, sulphonium methyl ketones and other potential inhibitors of cysteine proteinases

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7 January 2021

Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease.

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A simple method for organotypic cultures of nervous tissue

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7 January 2021

10.1016/S0304-3940(98)00364-4

Identifiers

DOI

1 reference

14 October 2017

1 reference