(Q41955062)

English

Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation

scientific article published on 31 August 2004

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

5

object named as

Brian W Matthews

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

Molly M He

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Zachary A Wood

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Walter A Baase

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Hong Xiao

4

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

publication date

31 August 2004

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Protein Science

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

13

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

10

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

2716-2724

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Electron-density map interpretation

1 reference

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5 June 2018

Raster3D Version 2.0. A program for photorealistic molecular graphics

1 reference

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5 June 2018

Repacking the Core of T4 lysozyme by automated design

1 reference

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5 June 2018

Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability

1 reference

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5 June 2018

A helix initiation signal in T4 lysozyme identified by polyalanine mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Crystal structures of a T4-lysozyme duplication-extension mutant demonstrate that the highly conserved beta-sheet region has low intrinsic folding propensity

1 reference

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5 June 2018

Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site

1 reference

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5 June 2018

Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability

1 reference

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Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding

1 reference

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5 June 2018

Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme

1 reference

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The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.

1 reference

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1 reference

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Seventy-five percent accuracy in protein secondary structure prediction

1 reference

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5 June 2018

Thermodynamic effects of mutations on the denaturation of T4 lysozyme

1 reference

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5 June 2018

Experimentally observed conformation-dependent geometry and hidden strain in proteins

1 reference

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5 June 2018

Structural and genetic analysis of the folding and function of T4 lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Structural basis of amino acid alpha helix propensity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

A thermodynamic scale for the beta-sheet forming tendencies of the amino acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

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Elucidating the folding problem of helical peptides using empirical parameters. II. Helix macrodipole effects and rational modification of the helical content of natural peptides.

1 reference

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5 June 2018

A relationship between protein stability and protein function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Stability of alpha-helices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

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Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

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Control of enzyme activity by an engineered disulfide bond

1 reference

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Second-site revertants of an inactive T4 lysozyme mutant restore activity by restructuring the active site cleft

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2286564

5 June 2018

Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence

1 reference

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Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect

1 reference

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5 June 2018

Multiple alanine replacements within α‐helix 126–134 of T4 lysozyme have independent, additive effects on both structure and stability

1 reference

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Collaborative Computational Project, number 4: providing programs for protein crystallography

1 reference

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Thermodynamic beta-sheet propensities measured using a zinc-finger host peptide.

1 reference

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Expression and nitrogen-15 labeling of proteins for proton and nitrogen-15 nuclear magnetic resonance

1 reference

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A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids

1 reference

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Crystallographic refinement by simulated annealing: methods and applications

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Genetic and structural analysis of the protein stability problem

1 reference

https://pubmed.ncbi.nlm.nih.gov/15340171

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based on heuristic

inferred from PubMed ID database lookup

Side chain contributions to the stability of alpha-helical structure in peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15340171

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the lysozyme from bacteriophage T4: An electron density map at 2.4 Å resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/15340171

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based on heuristic

inferred from PubMed ID database lookup

Context is a major determinant of β-sheet propensity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15340171

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1110/PS.04875504

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

ResearchGate publication ID

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