(Q41973810)

English

Immunohistochemical Estimates of Angiogenesis, Proliferative Activity, p53 Expression, and Multiple Drug Resistance Have No Prognostic Impact in Osteosarcoma: A Comparative Clinicopathological Investigation.

scientific article published on January 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Immunohistochemical Estimates of Angiogenesis, Proliferative Activity, p53 Expression, and Multiple Drug Resistance Have No Prognostic Impact in Osteosarcoma: A Comparative Clinicopathological Investigation (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

multiple drug resistance

1 reference

based on heuristic

inferred from title

immunohistochemistry

1 reference

based on heuristic

inferred from title

Flemming Brandt Sørensen

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Kenneth Jensen

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Michael Vaeth

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Henrik Hager

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Anette Mariane Daa Funder

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Johnny Keller

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Mariann Christensen

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

874075

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Proliferative activity (ki-67 expression) and outcome in high grade osteosarcoma: a study of 27 cases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma Intergroup.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Does the degree of intratumoural microvessel density and VEGF expression have prognostic significance in osteosarcoma?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Tumor heterogeneity affects the precision of microarray analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Prognostic relevance of increased angiogenesis in osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Second international consensus on the methodology and criteria of evaluation of angiogenesis quantification in solid human tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Lack of prognostic significance of intratumoral angiogenesis in nonmetastatic osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

The co-expression of p53 protein and P-glycoprotein is correlated to a poor prognosis in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Neuropilin-2 expression affects the increased vascularization and is a prognostic factor in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

P-glycoprotein levels predict poor outcome in patients with osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

p53/MDM-2 immunohistochemical expression correlated with proliferative activity in different subtypes of human sarcomas: a ten-year follow-up study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

P-glycoprotein and metallothionein expression and resistance to chemotherapy in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Blood vessel density in canine osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Positivity of the proliferation marker Ki-67 in noncycling cells

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

https://api.crossref.org/works/10.1155%2F2008%2F874075

21 January 2018

Quantitative analysis of multidrug resistance gene expression in human osteosarcomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Expression of p53 protein, PCNA, and Ki-67 in osteosarcomas of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Tumor size and prognosis in aggressively treated osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

New entities, concepts, and questions in childhood tumor pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

p53 expression and its relationship to DNA alterations in bone and soft tissue sarcomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Prognostic factors in osteosarcoma: a critical review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Correlation of p-glycoprotein detection by immunohistochemistry with mdr-1 mRNA levels in osteosarcomas. Pilot study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Suppression of pulmonary metastasis by angiogenesis inhibitor TNP-470 in murine osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Prognostic variables in osteosarcoma: a multi-institutional study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

5 June 2018

Tumor angiogenesis and outcome in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

Evaluation of P-glycoprotein, HER-2/ErbB-2, p53, and Bcl-2 in primary tumor and metachronous lung metastases in patients with high-grade osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

The association of P-glycoprotein with response to chemotherapy and clinical outcome in patients with osteosarcoma. A meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

Predictive factors of disease-free survival for non-metastatic osteosarcoma of the extremity: an analysis of 300 patients treated at the Rizzoli Institute

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

MDR1 gene expression and outcome in osteosarcoma: a prospective, multicenter study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

P-glycoprotein expression in osteosarcoma: a basis for risk-adapted adjuvant chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

Association of loss of heterozygosity at the p53 locus with chemoresistance in osteosarcomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

Alterations of the p53, Rb and MDM2 genes in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650184

18 August 2018

Expression of P-glycoprotein in high grade osteosarcomas with special emphasis on chondroblastic subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor expression in untreated osteosarcoma is predictive of pulmonary metastasis and poor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Correlation of tumor microvesseldensity with prognosis in osteogenic sarcoma]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic factors in osteosarcomas. A regression analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extraskeletal osteosarcomas: a clinicopathologic study of 25 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Cell proliferation in bone tumors. Immunohistologic study of Ki-67 protein expression]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Osteosarcoma--apoptosis and proliferation. Study of bcl-2 expression]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance and malignancy in human osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival, prognosis, and therapeutic response in osteogenic sarcoma. The memorial hospital experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance-1 gene expression does not increase during tumor progression in the MGH-OGS murine osteosarcoma tumor model

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of Ki-67 expression in bone tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 in tumour pathology: can we trust immunohistochemistry?--Revisited!

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of bax, bcl-2, and p53 staining in primary osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-grade intraosseous osteosarcoma in northern Japan: advantage of AgNOR and MIB-1 staining in differential diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation spectrum of the p53 gene in bone and soft tissue sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (AGM-1470) on osteosarcoma growth and lung metastasis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of growth factors and their receptors in human osteosarcomas. Immunohistochemical detection of epidermal growth factor, platelet-derived growth factor and their receptors: its correlation with proliferating activities and p53 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of HER2/erbB-2 correlates with survival in osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of histological changes and changes in nm23 and c-MET expression between primary and metastatic sites in osteosarcoma: a clinicopathologic and immunohistochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 and MDM2 alterations in osteosarcomas: correlation with clinicopathologic features and proliferative rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved grading of bone tumors with the monoclonal antibody Ki-67

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of P-glycoprotein expression in osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proliferation behavior of bone tumors investigated with the monoclonal antibody Ki-67

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 gene mutations in osteosarcomas of low-grade malignancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of p53 mutations in patients with localized osteosarcoma and metastatic osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of a combination of mitomycin, doxorubicin and cisplatin in advanced sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteosarcoma versus malignant fibrous histiocytoma of bone in patients older than 40 years. A clinicopathologic and immunohistochemical analysis with special reference to malignant fibrous histiocytoma-like osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein expression: critical determinant in the response to osteosarcoma chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of c-fos, p53, and PCNA expression with treatment outcome in osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Determination of the degree of morphological regression following chemotherapy in malignant bone tumors]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ki-67: a proliferative marker that may predict pulmonary metastases and mortality of primary osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein expression in high grade central osteosarcoma and normal bone cells. An immunohistochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histologic evaluation of necrosis in osteosarcoma induced by chemotherapy. Regional mapping of viable and nonviable tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of mutant P53 protein in osteosarcomas and other malignant and benign lesions of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19266050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2008/874075

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19266050%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

ResearchGate publication ID

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