(Q41977092)

English

Stereoselective central nervous system effects of the R- and S-isomers of the GABA uptake blocker N-(4, 4-di-(3-methylthien-2-yl)but-3-enyl) nipecotic acid in the rat.

scientific article published on December 1999

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Stereoselective central nervous system effects of the R- and S-isomers of the GABA uptake blocker N-(4, 4-di-(3-methylthien-2-yl)but-3-enyl) nipecotic acid in the rat. (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

stereoselectivity

1 reference

based on heuristic

inferred from title

Meindert Danhof

5

object named as

M Danhof

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

A Cleton

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

H J de Greef

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

P M Edelbroek

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

R A Voskuyl

4

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

0 references

publication date

1 December 1999

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

128

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

1651-1658

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

GABA and epileptogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

GABA transporter heterogeneity: pharmacology and cellular localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Estimating impossible curves using NONMEM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Quantitative autoradiographic characterization of the binding of [3H]tiagabine (NNC 05-328) to the GABA uptake carrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Clearance concepts in pharmacokinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

GABA synaptic mechanisms: stereochemical and conformational requirements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

GABA uptake inhibitors: relevance to antiepileptic drug research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Further evidence for abnormal GABAergic circuits in amygdala-kindled rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Semiparametric approach to pharmacokinetic-pharmacodynamic data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

(R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of heptabarbital using aperiodic EEG analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Effect of chirality on pharmacokinetics and pharmacodynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Inhibition by Neuroleptics of Uptake of 3H-GABA into Rat Brain Synaptosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

5 June 2018

Application of a combined "effect compartment/indirect response model" to the central nervous system effects of tiagabine in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571804

18 August 2018

High-performance liquid chromatographic procedure for the determination of tiagabine concentrations in human plasma using electrochemical detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/10588919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism-based pharmacodynamic modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/10588919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: an overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/10588919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new look at the statistical model identification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702962

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.BJP.0702962

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

ResearchGate publication ID

0 references

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