(Q41978368)

English

Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome

scientific article published on February 2006

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scholarly article

1 reference

Europe PubMed Central

14 October 2017

Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome (English)

1 reference

Europe PubMed Central

14 October 2017

substantia nigra

1 reference

based on heuristic

inferred from title

author name string

Chie Harashima

1

1 reference

Europe PubMed Central

14 October 2017

David M Jacobowitz

2

1 reference

Europe PubMed Central

14 October 2017

Jassir Witta

3

1 reference

Europe PubMed Central

14 October 2017

Rosemary C Borke

4

1 reference

Europe PubMed Central

14 October 2017

Tyler K Best

5

1 reference

Europe PubMed Central

14 October 2017

Richard J Siarey

6

1 reference

Europe PubMed Central

14 October 2017

Zygmunt Galdzicki

7

1 reference

Europe PubMed Central

14 October 2017

language of work or name

0 references

publication date

1 February 2006

1 reference

Europe PubMed Central

14 October 2017

The Journal of Comparative Neurology

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Europe PubMed Central

14 October 2017

494

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Europe PubMed Central

14 October 2017

5

1 reference

Europe PubMed Central

14 October 2017

815-833

1 reference

Europe PubMed Central

14 October 2017

A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Understanding mental retardation in Down's syndrome using trisomy 16 mouse models

1 reference

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5 June 2018

Down's syndrome: a genetic disorder in biobehavioral perspective

1 reference

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5 June 2018

The neuropsychology of Down syndrome: evidence for hippocampal dysfunction

1 reference

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5 June 2018

Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory

1 reference

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Comparative genomic sequence analysis of the human chromosome 21 Down syndrome critical region

1 reference

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Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart

1 reference

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Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

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Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

1 reference

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Co-expression of human Kir3 subunits can yield channels with different functional properties

1 reference

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Neuronal inwardly rectifying K(+) channels differentially couple to PDZ proteins of the PSD-95/SAP90 family

1 reference

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5 June 2018

Anchoring proteins confer G protein sensitivity to an inward-rectifier K(+) channel through the GK domain

1 reference

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5 June 2018

Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3.

1 reference

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5 June 2018

A murine model for Down syndrome shows reduced responsiveness to pain.

1 reference

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5 June 2018

GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels

1 reference

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5 June 2018

G protein regulation of potassium ion channels

1 reference

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5 June 2018

Identification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimers

1 reference

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New therapeutic approaches to cognitive impairment.

1 reference

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5 June 2018

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

1 reference

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5 June 2018

Electrical and calcium signaling in dendrites of hippocampal pyramidal neurons

1 reference

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5 June 2018

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome

1 reference

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5 June 2018

Number and stoichiometry of subunits in the native atrial G-protein-gated K+ channel, IKACh

1 reference

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5 June 2018

Developmental expression of the GIRK family of inward rectifying potassium channels: implications for abnormalities in the weaver mutant mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Signalling via the G protein-activated K+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

K+ channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons

1 reference

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5 June 2018

Inwardly rectifying potassium channels: their molecular heterogeneity and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Reduced expression of voltage-gated sodium channels in neurons cultured from trisomy 16 mouse hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Interneurons of the hippocampus

1 reference

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5 June 2018

Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model.

1 reference

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5 June 2018

Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: altered behavior in the elevated plus maze and open field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Nonselective and G betagamma-insensitive weaver K+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

G protein-gated K+ channel (GIRK1) protein is expressed presynaptically in the paraventricular nucleus of the hypothalamus.

1 reference

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5 June 2018

Advanced maternal age and the risk of Down syndrome characterized by the meiotic stage of chromosomal error: a population-based study.

1 reference

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5 June 2018

IRK(1-3) and GIRK(1-4) inwardly rectifying K+ channel mRNAs are differentially expressed in the adult rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

Down syndrome phenotypes: the consequences of chromosomal imbalance

1 reference

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5 June 2018

Epilepsy in Down syndrome: clinical aspects and possible mechanisms.

1 reference

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5 June 2018

Distribution and localization of a G protein-coupled inwardly rectifying K+ channel in the rat.

1 reference

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5 June 2018

Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain

1 reference

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5 June 2018

Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain

1 reference

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5 June 2018

Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

5 June 2018

A mouse model for Down syndrome exhibits learning and behaviour deficits.

1 reference

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5 June 2018

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

1 reference

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5 June 2018

Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels.

1 reference

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Ion channel regulation by G proteins.

1 reference

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5 June 2018

Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice

1 reference

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5 June 2018

The development of the pathologic changes of Alzheimer's disease and senile dementia in patients with Down's syndrome

1 reference

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Structural abnormalities of the cerebral cortex in human chromosomal aberrations: a Golgi study.

1 reference

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Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

1 reference

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The topography of plaques and tangles in Down's syndrome patients of different ages

1 reference

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5 June 2018

Tonic/clonic seizures in a mouse mutant carrying the weaver gene

1 reference

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5 June 2018

Down syndrome: toward a molecular definition of the phenotype.

1 reference

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5 June 2018

Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome

1 reference

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5 June 2018

Protocols to establish genotype-phenotype correlations in Down syndrome

1 reference

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BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone.

1 reference

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5 June 2018

Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons.

1 reference

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18 August 2018

Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.

1 reference

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Minocycline prevents cholinergic loss in a mouse model of Down's syndrome

1 reference

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The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus

1 reference

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18 August 2018

Chromosome 21 KIR channels in brain development.

1 reference

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Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia.

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Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system

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18 August 2018

Contribution of Kir3.1, Kir3.2A and Kir3.2C subunits to native G protein‐gated inwardly rectifying potassium currents in cultured hippocampal neurons

1 reference

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18 August 2018

Special interest section--Down's syndrome: postgenomic approaches to neurobiological problems.

1 reference

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18 August 2018

Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.

1 reference

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18 August 2018

Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome.

1 reference

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18 August 2018

Interplay between activation of GIRK current and deactivation of Ih modifies temporal integration of excitatory input in CA1 pyramidal cells

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18 August 2018

Measurement of dorsal root ganglion P2X mRNA by SYBR Green fluorescence.

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18 August 2018

G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons.

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18 August 2018

Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.

1 reference

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18 August 2018

Relation of medial temporal lobe volumes to age and memory function in nondemented adults with Down's syndrome: implications for the prodromal phase of Alzheimer's disease.

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18 August 2018

Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study.

1 reference

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18 August 2018

Motor learning in Ts65Dn mice, a model for Down syndrome.

1 reference

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18 August 2018

Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome

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18 August 2018

Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice.

1 reference

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18 August 2018

Motor dysfunction in a mouse model for Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Characterization of murine Girk2 transcript isoforms: structure and differential expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Cholinergic, serotonergic and catecholaminergic neurons are not affected in Ts65Dn mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Responses to NMDA in cultured hippocampal neurons from trisomy 16 embryonic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Spatial memory deficits in segmental trisomic Ts65Dn mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

G-protein-gated inward rectifier K+ channel proteins (GIRK1) are present in the soma and dendrites as well as in nerve terminals of specific neurons in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

A behavioral assessment of Ts65Dn mice: a putative Down syndrome model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Dopamine deficiency in the weaver mutant mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

Defects in specific associations between astroglia and neurons occur in microcultures of weaver mouse cerebellar cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929960

18 August 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNE.20844

21 January 2018

Parental origin of the extra chromosome in trisomy 21 as indicated by analysis of DNA polymorphisms. Down Syndrome Collaborative Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and nonlimbic striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse trisomy 16: an animal model of human trisomy 21 (Down syndrome)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Molecular and biophysical aspects of potassium channels]

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mRNA at the synapse: analysis of a synaptosomal preparation enriched in hippocampal dendritic spines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ts65Dn mouse, a Down syndrome model, exhibits elevated myo-inositol in selected brain regions and peripheral tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models

1 reference

https://pubmed.ncbi.nlm.nih.gov/16374808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/CNE.20844

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

ResearchGate publication ID

0 references

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