(Q48354682)

10 February 2018

title

Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome. (English)

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10 February 2018

author name string

Christopher L Hunter

1

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10 February 2018

Ole Isacson

2

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10 February 2018

Matthew Nelson

3

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10 February 2018

Heather Bimonte-Nelson

4

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10 February 2018

Hyemyung Seo

5

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10 February 2018

Ling Lin

6

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10 February 2018

Kerstin Ford

7

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10 February 2018

Mark S Kindy

8

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10 February 2018

Ann-Charlotte Granholm

9

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10 February 2018

publication date

1 April 2003

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10 February 2018

published in

Neuroscience Research

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10 February 2018

volume

45

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10 February 2018

issue

4

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10 February 2018

page(s)

437-445

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10 February 2018

Amyloid precursor protein modulates the interaction of nerve growth factor with p75 receptor and potentiates its activation of trkA phosphorylation

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Differential patterns of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNA and protein levels in developing regions of rat brain.

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Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model.

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Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome

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Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

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7 January 2021

Estrogen alters amyloid precursor protein as well as dendritic and cholinergic markers in a mouse model of Down syndrome.

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7 January 2021

Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome

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7 January 2021

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

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7 January 2021

Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory

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7 January 2021

Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function.

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7 January 2021

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7 January 2021

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7 January 2021

The cholinergic system in Alzheimer's disease

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7 January 2021

Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice

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7 January 2021

Down syndrome phenotypes: the consequences of chromosomal imbalance

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7 January 2021

Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice.

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7 January 2021

The cognitive psychopharmacology of Alzheimer's disease: focus on cholinergic systems

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7 January 2021

Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

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7 January 2021

Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism

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7 January 2021

Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey

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7 January 2021

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

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7 January 2021

Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis.

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7 January 2021

Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases

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7 January 2021

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

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7 January 2021

Alzheimer's disease: a dysfunction of the amyloid precursor protein(1).

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7 January 2021

The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity

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7 January 2021

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

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7 January 2021

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7 January 2021

A mouse model for Down syndrome exhibits learning and behaviour deficits.

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7 January 2021

Cholinergic control of nerve growth factor in adult rats: evidence from cortical cholinergic deafferentation and chronic drug treatment.

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7 January 2021

Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis

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7 January 2021

Translating cell biology into therapeutic advances in Alzheimer's disease

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7 January 2021

Reduction in TrkA-immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2803%2900005-1

7 January 2021

Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2803%2900005-1

7 January 2021

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2803%2900005-1

7 January 2021

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2803%2900005-1

7 January 2021

Amyloid precursor protein potentiates the neurotrophic activity of NGF.

1 reference

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7 January 2021

An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues

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7 January 2021

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

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7 January 2021

Alzheimer-like cholinergic deficiency in Down syndrome

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7 January 2021

10.1016/S0168-0102(03)00005-1

Identifiers

DOI

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10 February 2018

PubMed ID

12657457

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10 February 2018