(Q41979327)

14 October 2017

Asimadoline, a kappa-opioid agonist, and satiation in functional dyspepsia (English)

1 reference

14 October 2017

5

A R Zinsmeister

1 reference

14 October 2017

1

N J Talley

1 reference

14 October 2017

R S Choung

2

1 reference

14 October 2017

M Camilleri

series ordinal

3

1 reference

14 October 2017

R A Dierkhising

series ordinal

4

1 reference

14 October 2017

language of work or name

English

0 references

publication date

7 March 2008

1 reference

Alimentary Pharmacology & Therapeutics

14 October 2017

1 reference

14 October 2017

27

1 reference

14 October 2017

11

1 reference

14 October 2017

1122-1131

1 reference

Efficacy of on-demand asimadoline, a peripheral kappa-opioid agonist, in females with irritable bowel syndrome

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Ligands regulate cell surface level of the human kappa opioid receptor by activation-induced down-regulation and pharmacological chaperone-mediated enhancement: differential effects of nonpeptide and peptide agonists

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Peripheral opioids for functional GI disease: a reappraisal

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Functional gastroduodenal disorders

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Novel developments with selective, non-peptidic kappa-opioid receptor agonists

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Function of opioids in the enteric nervous system

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Effect of asimadoline, a kappa opioid agonist, on pain induced by colonic distension in patients with irritable bowel syndrome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Agonist-induced regulation and trafficking of kappa opioid receptors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Diet, food intake, and disturbed physiology in the pathogenesis of symptoms in functional dyspepsia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Effects of a kappa-opioid agonist, asimadoline, on satiation and GI motor and sensory functions in humans

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Do changes in visceral sensory function determine the development of dyspepsia during treatment with aspirin?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Irritable bowel syndrome neuropharmacology. A review of approved and investigational compounds

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Influence of asimadoline, a new kappa-opioid receptor agonist, on tubular water absorption and vasopressin secretion in man.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Differences in gastric mechanosensory function after repeated ramp distensions in non-consulters with dyspepsia and healthy controls

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Gastric accommodation in non-ulcer dyspepsia and the roles of Helicobacter pylori infection and vagal function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Symptoms and visceral perception in severe functional and organic dyspepsia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Effects of kappa-opioid receptor agonists on responses to colorectal distension in rats with and without acute colonic inflammation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Brain concentrations of asimadoline in mice: the influence of coadministration of various P-glycoprotein substrates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Efficacy and safety of the peripheral kappa agonist fedotozine versus placebo in the treatment of functional dyspepsia.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Fedotozine blocks hypersensitive visceral pain in conscious rats: action at peripheral kappa-opioid receptors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Impaired accommodation of proximal stomach to a meal in functional dyspepsia.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

A pharmacological profile of the novel, peripherally-selective kappa-opioid receptor agonist, EMD 61753.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

The hospital anxiety and depression scale

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Effect of chronic administration of U-50,488H on tolerance to its pharmacological actions and on multiple opioid receptors in rat brain regions and spinal cord

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Neurohormonal factors in functional dyspepsia: insights on pathophysiological mechanisms

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

A Bowel Symptom Questionnaire for the Elderly

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Fasting and postprandial gastrointestinal motility in ulcer and non-ulcer dyspepsia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Effects of venlafaxine, buspirone, and placebo on colonic sensorimotor functions in healthy humans

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Effects of asimadoline, a kappa-opioid agonist, on satiation and postprandial symptoms in health

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Quality of life in functional dyspepsia: responsiveness of the Nepean Dyspepsia Index and development of a new 10-item short form.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

kappa-opioid receptor-mediated analgesia: hotplate temperature and sex differences

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Fedotozine, a kappa-opioid agonist, prevents spinal and supra-spinal Fos expression induced by a noxious visceral stimulus in the rat.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Abnormal clearance of exogenous acid and increased acid sensitivity of the proximal duodenum in dyspeptic patients.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Kappa-opioids produce significantly greater analgesia in women than in men.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Kappa, but not mu or delta, opioids attenuate responses to distention of afferent fibers innervating the rat colon.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

kappa-Opioid activity of the four stereoisomers of the peripherally selective kappa-agonists, EMD 60,400 and EMD 61,753.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935285

Quality of life in patients with upper gastrointestinal symptoms. An improved evaluation of treatment regimens?

18 August 2018

1 reference

12 December 2020

Symptoms associated with hypersensitivity to gastric distention in functional dyspepsia

1 reference

12 December 2020

Effect of the kappa agonist fedotozine on perception of gastric distension in healthy humans

1 reference

12 December 2020

Association of the predominant symptom with clinical characteristics and pathophysiological mechanisms in functional dyspepsia

1 reference

12 December 2020

Effects of kappa opioids in the inflamed rat colon

1 reference

12 December 2020

Intolerance to visceral distension in functional dyspepsia or irritable bowel syndrome: an organ specific defect or a pan intestinal dysregulation?

1 reference

12 December 2020

Role of impaired gastric accommodation to a meal in functional dyspepsia

1 reference

12 December 2020

Double-blind dose-response multicenter comparison of fedotozine and placebo in treatment of nonulcer dyspepsia

1 reference

12 December 2020

Abnormal perception of visceral pain in response to gastric distension in chronic idiopathic dyspepsia. The irritable stomach syndrome

1 reference

12 December 2020

Effect of gender on anti-inflammatory and analgesic actions of two kappa-opioids

1 reference

12 December 2020

10.1111/J.1365-2036.2008.03676.X

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

18331462

1 reference