(Q41988947)

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Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.

scientific article published on May 2011

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scholarly article

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29 January 2020

Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice (English)

1 reference

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29 January 2020

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Pranoti S. Mandrekar

8

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29 January 2020

author name string

Bharath Nath

1

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29 January 2020

Ivan Levin

2

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29 January 2020

Timea Csak

3

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29 January 2020

Jan Petrasek

4

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29 January 2020

Christian Mueller

5

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29 January 2020

Karen Kodys

6

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29 January 2020

Donna Catalano

7

1 reference

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29 January 2020

Gyongyi Szabo

9

1 reference

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29 January 2020

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publication date

1 May 2011

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29 January 2020

1 reference

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29 January 2020

53

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29 January 2020

5

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29 January 2020

1526-1537

1 reference

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29 January 2020

Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Alcohol-induced modulation of signaling pathways in liver parenchymal and nonparenchymal cells: implications for immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Chronic ethanol feeding to rats decreases adiponectin secretion by subcutaneous adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-Met

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

5 June 2018

The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Effect of chronic alcohol consumption on Hepatic SIRT1 and PGC-1alpha in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor alpha/retinoid X receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Is the hypoxia-inducible factor-1 alpha mRNA expression activated by ethanol-induced injury, the mechanism underlying alcoholic liver disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Kupffer cell sensitization by alcohol involves increased permeability to gut-derived endotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104403

18 August 2018

Acute alcohol produces hypoxia directly in rat liver tissue in vivo: role of Kupffer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21520168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21520168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia Converts Human Macrophages Into Triglyceride-Loaded Foam Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21520168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of hypoxia in the pathogenesis of alcoholic liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21520168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the peroxisome proliferator-activated receptor gene is decreased in experimental alcoholic liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21520168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24256

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HEP.24256

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21520168%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21520168%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21520168%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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