(Q41990410)

English

A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading

scientific article published on 13 February 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

1 reference

based on heuristic

inferred from title

author name string

Daniel P Kane

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Polina V Shcherbakova

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

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publication date

13 February 2014

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Europe PubMed Central

PMC publication ID

14 October 2017

Cancer Research

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Europe PubMed Central

PMC publication ID

14 October 2017

74

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Europe PubMed Central

PMC publication ID

14 October 2017

7

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

1895-1901

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase

1 reference

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The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology

1 reference

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5 June 2018

Integrated genomic characterization of endometrial carcinoma

1 reference

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DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer

1 reference

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Impact of deleterious passenger mutations on cancer progression

1 reference

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5 June 2018

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

1 reference

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Recurrent R-spondin fusions in colon cancer

1 reference

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Comprehensive molecular characterization of human colon and rectal cancer

1 reference

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Mutator suppression and escape from replication error-induced extinction in yeast

1 reference

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5 June 2018

A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability

1 reference

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5 June 2018

DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice

1 reference

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Mutational heterogeneity in human cancers: origin and consequences.

1 reference

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5 June 2018

DNA polymerase proofreading: Multiple roles maintain genome stability

1 reference

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Genetic predisposition to colorectal cancer

1 reference

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Mouse models for human DNA mismatch-repair gene defects

1 reference

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5 June 2018

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310866

5 June 2018

Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310866

5 June 2018

Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310866

5 June 2018

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

1 reference

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5 June 2018

Identifiers

10.1158/0008-5472.CAN-13-2892

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

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