(Q42021514)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

4 February 2021

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

5 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

20 June 2019

1 reference

1 reference

4 February 2021

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Joshua A. Beckman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Francesco Paneni

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Mark A Creager

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

1 reference

2 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 August 2013

1 reference

4 February 2021

European Heart Journal

7 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

20 June 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

4 February 2021

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

2436-2443

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

29 February 2020

copyright license

6 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

20 June 2019

on focus list of Wikimedia project

4 February 2021

ScienceSource

0 references

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The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: an update

5 June 2018

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Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin

5 June 2018

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Role of microRNAs in diabetes and its cardiovascular complications.

5 June 2018

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Adipokines in inflammation, insulin resistance and cardiovascular disease

5 June 2018

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Current concepts on coronary revascularization in diabetic patients

5 June 2018

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MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus

5 June 2018

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Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials

5 June 2018

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Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction

5 June 2018

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Blood pressure, lipids and glucose in type 2 diabetes: how low should we go? Re-discovering personalized care

5 June 2018

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New insights into insulin resistance in the diabetic heart

5 June 2018

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Efficacy of fibrates for cardiovascular risk reduction in persons with atherogenic dyslipidemia: a meta-analysis

5 June 2018

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MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damage

5 June 2018

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Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia

5 June 2018

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Oxidative stress and diabetic complications

5 June 2018

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Diabetics with acute coronary syndrome: advances, challenges, and uncertainties

5 June 2018

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Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes

5 June 2018

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Hyperglycemia: a prothrombotic factor?

5 June 2018

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Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice

5 June 2018

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Activation of protein kinase C isoforms and its impact on diabetic complications

5 June 2018

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The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature

5 June 2018

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Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

5 June 2018

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Macrophages, inflammation, and insulin resistance

5 June 2018

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Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice.

5 June 2018

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MicroRNA Regulation and its Biological Significance in Personalized Medicine and Aging

5 June 2018

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MicroRNA-221 regulates high glucose-induced endothelial dysfunction

5 June 2018

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Glucose control and vascular complications in veterans with type 2 diabetes

5 June 2018

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The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia

5 June 2018

1 reference

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p53 impairs endothelium-dependent vasomotor function through transcriptional upregulation of p66shc.

5 June 2018

1 reference

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MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats

5 June 2018

1 reference

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Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

5 June 2018

1 reference

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10-year follow-up of intensive glucose control in type 2 diabetes

5 June 2018

1 reference

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Effects of intensive glucose lowering in type 2 diabetes

5 June 2018

1 reference

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Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes

5 June 2018

1 reference

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Novel biochemical risk factors for type 2 diabetes: pathogenic insights or prediction possibilities?

5 June 2018

1 reference

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Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein.

5 June 2018

1 reference

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Diabetes mellitus as a prothrombotic condition

5 June 2018

1 reference

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Effects of hyperglycemia and hyperinsulinemia on the tissue factor pathway of blood coagulation

5 June 2018

1 reference

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Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling

5 June 2018

1 reference

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Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.

5 June 2018

1 reference

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Obesity and diabetes in the developing world--a growing challenge

5 June 2018

1 reference

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Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system

5 June 2018

1 reference

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Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms.

5 June 2018

1 reference

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Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Hexosamines, insulin resistance, and the complications of diabetes: current status

5 June 2018

1 reference

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Understanding RAGE, the receptor for advanced glycation end products

5 June 2018

1 reference

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Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Endothelial function: cardiac events

5 June 2018

1 reference

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Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

5 June 2018

1 reference

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Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Report of the expert committee on the diagnosis and classification of diabetes mellitus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Diabetes and atherosclerosis: epidemiology, pathophysiology, and management

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Insulin signalling and the regulation of glucose and lipid metabolism

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Platelet dysfunction in type 2 diabetes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Mechanisms underlying endothelial dysfunction in diabetes mellitus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Cellular mechanisms of insulin resistance

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Contributions of polyol pathway to oxidative stress in diabetic cataract.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Effects of diabetes and level of glycemia on all-cause and cardiovascular mortality. The San Antonio Heart Study

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Rosiglitazone improves endothelial function in patients with type 2 diabetes treated with insulin.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Circulating CD31+/Annexin V+ microparticles correlate with cardiovascular outcomes

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Hypothesis: the "metabolic memory", the new challenge of diabetes

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Simultaneous control of hyperglycemia and oxidative stress normalizes enhanced thrombin generation in type 1 diabetes.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Dysglycaemia, cardiovascular outcome and treatment. Is the jury still out?

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Usefulness of atherogenic dyslipidemia for predicting cardiovascular risk in patients with angiographically defined coronary artery disease.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Insulin resistance as a determinant of platelet activation in obese women.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Effects of hyperglycemia and hyperinsulinemia on circulating tissue factor procoagulant activity and platelet CD40 ligand

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Platelet inhibition by insulin is absent in type 2 diabetes mellitus

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Metformin improves endothelial function in patients with metabolic syndrome.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Selective inhibition of protein kinase Cbeta2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Increased activity of endogenous endothelin in patients with type II diabetes mellitus

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Relation of improvement in endothelium-dependent flow-mediated vasodilation after rosiglitazone to changes in asymmetric dimethylarginine, endothelin-1, and C-reactive protein in nondiabetic patients with the metabolic syndrome

17 August 2018

1 reference

12 December 2020

Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1

1 reference

12 December 2020

Involvement of microparticles in diabetic vascular complications

1 reference

12 December 2020

The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes

1 reference

12 December 2020

Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs life spans

1 reference

12 December 2020

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

1 reference

12 December 2020

Endothelial nuclear factor κB in obesity and aging: is endothelial nuclear factor κB a master regulator of inflammation and insulin resistance?

1 reference

12 December 2020

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

1 reference

12 December 2020

High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1093/EURHEARTJ/EHT149

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json