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Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.
scientific article published on 31 March 2014
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PMC publication ID
4101147
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24688021%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
title
Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins
(English)
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PMC publication ID
4101147
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24688021%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
main subject
hypoxia
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Fanconi anemia
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inferred from title
author
Susan Scanlon
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1
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Europe PubMed Central
PMC publication ID
4101147
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24688021%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
Peter M Glazer
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2
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4101147
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12 March 2020
author name string
Susan E Scanlon
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1
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PMC publication ID
4101147
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15 October 2017
Peter M Glazer
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2
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PMC publication ID
4101147
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15 October 2017
publication date
31 March 2014
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4101147
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12 March 2020
published in
Molecular Cancer Research
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PMC publication ID
4101147
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12 March 2020
volume
12
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Europe PubMed Central
PMC publication ID
4101147
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12 March 2020
issue
7
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4101147
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12 March 2020
page(s)
1016-1028
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4101147
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12 March 2020
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New aspects on chromosomal instability: chromosomal break-points in Fanconi anemia patients co-localize on the molecular level with fragile sites
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Fanconi anemia proteins stabilize replication forks
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Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway
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Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
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Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair
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Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin
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Oxygen sensing by HIF hydroxylases
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Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells
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5 June 2018
A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs
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Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells
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5 June 2018
FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.
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Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.
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17 August 2018
The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability
1 reference
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PubMed Central
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17 August 2018
Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest
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17 August 2018
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1541-7786.MCR-13-0628
1 reference
stated in
Europe PubMed Central
PMC publication ID
4101147
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24688021%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PMC publication ID
4101147
1 reference
stated in
Europe PubMed Central
PMC publication ID
4101147
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24688021%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PubMed publication ID
24688021
1 reference
stated in
Europe PubMed Central
PMC publication ID
4101147
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24688021%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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