(Q42027608)

English

Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias

scientific article published on 26 November 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

object named as

Xiongwen Chen

15

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Jeffery D. Molkentin

object named as

Jeffery D Molkentin

14

0 references

author name string

Xiaoying Zhang

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Xiaojie Ai

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Hiroyuki Nakayama

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Biyi Chen

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

David M Harris

5

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Mingxin Tang

6

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Yuping Xie

7

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Christopher Szeto

8

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Yingxin Li

9

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Ying Li

10

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Hongyu Zhang

11

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Andrea D Eckhart

12

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Walter J Koch

13

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

publication date

26 November 2015

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Basic Research in Cardiology

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

111

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Electrical remodeling in the failing heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

The genetic basis of long QT and short QT syndromes: a mutation update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Targeting calcium handling in arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Chronic verapamil treatment remodels ICa,L in mouse ventricle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Calmodulin kinase and L-type calcium channels; a recipe for arrhythmias?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Studying cardiac arrhythmias in the mouse--a reasonable model for probing mechanisms?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Regulation of cardiac excitation-contraction coupling by action potential repolarization: role of the transient outward potassium current (I(to)).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Cardiac excitation-contraction coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Voltage sensing and activation gating of HCN pacemaker channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Myocardial potassium channels: electrophysiological and molecular diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Beta-adrenergic function in heart muscle disease and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Afterdepolarizations and triggered activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

5 June 2018

Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Ca2+ influx-induced sarcoplasmic reticulum Ca2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

The effects of intracellular Ca2+ on cardiac K+ channel expression and activity: novel insights from genetically altered mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Ca2+ controls functional expression of the cardiac K+ transient outward current via the calcineurin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Action potential duration determines sarcoplasmic reticulum Ca2+ reloading in mammalian ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Electrical remodeling in hearts from a calcium-dependent mouse model of hypertrophy and failure: complex nature of K+ current changes and action potential duration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Action potential prolongation in cardiac myocytes of old rats is an adaptation to sustain youthful intracellular Ca2+ regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Direct measurement of SR release flux by tracking 'Ca2+ spikes' in rat cardiac myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4876110

17 August 2018

Calcineurin Increases Cardiac Transient Outward K+Currents via Transcriptional Up-regulation of Kv4.2 Channel Subunits

1 reference

https://api.crossref.org/works/10.1007%2FS00395-015-0523-4

21 January 2018

Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611208

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611208

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin kinase II inhibition shortens action potential duration by upregulation of K+ currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/26611208

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00395-015-0523-4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

0 references

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