(Q42050247)

15 October 2017

Chemical properties which control selectivity and efficacy of aromatic N-oxide bioreductive drugs (English)

1 reference

15 October 2017

7

I J Stratford

1 reference

15 October 2017

P Wardman

1

1 reference

15 October 2017

K I Priyadarsini

2

1 reference

15 October 2017

M F Dennis

3

1 reference

15 October 2017

S A Everett

4

1 reference

15 October 2017

M A Naylor

5

1 reference

15 October 2017

K B Patel

6

1 reference

15 October 2017

M R Stratford

8

1 reference

15 October 2017

M Tracy

9

1 reference

15 October 2017

1 July 1996

1 reference

The British Journal of Cancer. Supplement

15 October 2017

1 reference

15 October 2017

27

1 reference

15 October 2017

S70-4

1 reference

The experimental development of bioreductive drugs and their role in cancer therapy.

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

Radiation chemistry applied to drug design

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

Novel N-oxides as bioreductive drugs.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

Structure-activity relationships for benzotriazine di-N-oxides

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

Repair of DNA and chromosome breaks in cells exposed to SR 4233 under hypoxia or to ionizing radiation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

Pulse radiolysis and drug design

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2150009

Electrochemical studies of tirapazamine: generation of the one-electron reduction product

5 June 2018

1 reference

12 December 2020

Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233)

1 reference

12 December 2020

The reduction potential of benzyl viologen: an important reference compound for oxidant/radical redox couples

1 reference

12 December 2020

Second-generation 1,2,4-benzotriazine 1,4-di-N-oxide bioreductive anti-tumor agents: pharmacology and activity in vitro and in vivo

1 reference

12 December 2020

Free radical intermediates in the oxidation of flavone-8-acetic acid: possible involvement in its antitumour activity

1 reference

12 December 2020

Heterocyclic mono-N-oxides with potential applications as bioreductive anti-tumour drugs: Part 1. 8-Alkylamino-substituted phenylimidazo [1,2-a] quinoxalines

1 reference

12 December 2020

Radiolytic and photochemical reduction of the hypoxic cytotoxin 1,2-dihydro-8-(4-methylpiperazinyl)-4-phenylimidazo [1,2-a] pyrido [3,2-e] pyrazine 5-oxide (RB90740) and a potential mechanism for hypoxia-selective toxicity

1 reference

12 December 2020

Identifiers

1 reference

15 October 2017

PubMed publication ID

8763850

1 reference