(Q42059862)

English

Molecular and structural basis for the roles of hepatitis C virus polymerase NS5B amino acids 15, 223, and 321 in viral replication and drug resistance

scientific article published on 2 September 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Molecular and structural basis for the roles of hepatitis C virus polymerase NS5B amino acids 15, 223, and 321 in viral replication and drug resistance (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Hepatitis C virus

1 reference

based on heuristic

inferred from title

Thomas E Edwards

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

author name string

Angela M Lam

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Ralph T Mosley

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Eisuke Murakami

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Shalini Bansal

5

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Christopher Lugo

6

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Haiying Bao

7

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Michael J Otto

8

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Michael J Sofia

9

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Phillip A Furman

10

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

language of work or name

0 references

publication date

2 September 2014

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

58

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

11

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

6861-6869

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Nucleotide prodrugs for the treatment of HCV infection

1 reference

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5 June 2018

Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Hepatitis C virus nucleotide inhibitors PSI-352938 and PSI-353661 exhibit a novel mechanism of resistance requiring multiple mutations within replicon RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes

1 reference

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5 June 2018

Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

1 reference

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5 June 2018

Structural and Functional Analysis of Hepatitis C Virus Strain JFH1 Polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Phasercrystallographic software

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Hepatitis C virus subgenomic replicon requires an active NS3 RNA helicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

5 June 2018

HCV RNA-dependent RNA polymerase replicates in vitro the 3' terminal region of the minus-strand viral RNA more efficiently than the 3' terminal region of the plus RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249362

17 August 2018

Identifiers

10.1128/AAC.03847-14

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

0 references

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