(Q420604)

Phenylalanine-4-hydroxylase, tetrameric form

1 reference

Aromatic amino acid hydroxylase superfamily

1 reference

Aromatic amino acid hydroxylase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ACT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aromatic amino acid hydroxylase, iron/copper binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

phenylalanine 4-monooxygenase activity

6 references

27 March 2018

Gene transfer and expression of human phenylalanine hydroxylase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

27 March 2018

Activation of phenylalanine hydroxylase induces positive cooperativity toward the natural cofactor

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

27 March 2018

Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

oxidoreductase activity

1 reference

8 April 2019

phenylalanine 4-monooxygenase activity

7 references

7 November 2018

Gene transfer and expression of human phenylalanine hydroxylase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

7 November 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

7 November 2018

Activation of phenylalanine hydroxylase induces positive cooperativity toward the natural cofactor

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

7 November 2018

Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00439&geneProductId=UniProtKB:P00439

phenylalanine 4-monooxygenase activity

EXP

6 references

8 April 2019

Gene transfer and expression of human phenylalanine hydroxylase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

8 April 2019

Activation of phenylalanine hydroxylase induces positive cooperativity toward the natural cofactor

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

catecholamine biosynthetic process

TAS

biological process

1 reference

8 April 2019

Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

neurotransmitter biosynthetic process

NAS

1 reference

8 April 2019

Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

cellular amino acid biosynthetic process

NAS

1 reference

8 April 2019

Gene transfer and expression of human phenylalanine hydroxylase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

aromatic amino acid family metabolic process

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

tyrosine biosynthetic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00439

physically interacts with

IBA

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5240

sapropterin dihydrochloride

English

retrieved

17 August 2016

object has role

activation

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201775

Gene Atlas image

PBB GE PAH 205719 s at fs.png
732 × 530; 11 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P00439

1 reference

Aromatic amino acid hydroxylase, iron/copper binding site

Identifiers.org

has part(s)

1 reference

ACT domain

1 reference

Aromatic amino acid hydroxylase, C-terminal

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Identifiers

MeSH descriptor ID

D010651

subject named as

Phenylalanine Hydroxylase

0 references

MeSH tree code

D08.811.682.690.708.601

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

0 references

1 reference