(Q42081115)

English

Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells (English)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Warren Fiskus

1

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Kate Buckley

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Rekha Rao

3

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Aditya Mandawat

4

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Yonghua Yang

5

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Rajeshree Joshi

6

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Yongchao Wang

7

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Ramesh Balusu

8

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Jianguang Chen

9

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Sanjay Koul

10

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Atul Joshi

11

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Sunil Upadhyay

12

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Peter Atadja

13

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Kapil N Bhalla

14

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

publication date

18 May 2009

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Cancer Biology and Therapy

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

10

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

939-950

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2775142/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells.

1 reference

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Roles of the EZH2 histone methyltransferase in cancer epigenetics

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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30 May 2018

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1 reference

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Histone deacetylase inhibitors: overview and perspectives

1 reference

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1 reference

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1 reference

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30 May 2018

DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.

1 reference

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30 May 2018

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

1 reference

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JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas

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30 May 2018

Genome regulation by polycomb and trithorax proteins

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The mammalian epigenome

1 reference

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30 May 2018

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

1 reference

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Polycomb silencing mechanisms and the management of genomic programmes

1 reference

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Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775142

30 May 2018

Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells

1 reference

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Polycomb silencers control cell fate, development and cancer

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DNA methyltransferase 1 knockdown activates a replication stress checkpoint.

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Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against Bcr-Abl-expressing human leukemia cells

1 reference

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30 May 2018

The Polycomb group protein EZH2 directly controls DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775142

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EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

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30 May 2018

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

1 reference

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Methylation silencing of the Apaf-1 gene in acute leukemia

1 reference

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Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate

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1 reference

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1 reference

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1 reference

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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

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Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin.

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17 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279403

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279403

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279403

12 December 2020

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inferred from PubMed ID database lookup

Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279403

12 December 2020

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inferred from PubMed ID database lookup

Trichostatin A down-regulate DNA methyltransferase 1 in Jurkat T cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CBT.8.10.8213

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

ResearchGate publication ID

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