(Q53544194)

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Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17596871%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17596871%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

RNA interference

1 reference

based on heuristic

inferred from title

9

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1 January 2020

10

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1 January 2020

11

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1 January 2020

1

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Yangchao Chen

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1 January 2020

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Marie C Lin

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1 January 2020

Hong Yao

3

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1 January 2020

Hua Wang

4

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1 January 2020

Ai-Qun Zhang

5

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1 January 2020

Jun Yu

6

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1 January 2020

Chee-kin Hui

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1 January 2020

George K Lau

8

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1 January 2020

Hsiang-fu Kung

12

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1 January 2020

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1 July 2007

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1 January 2020

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1 January 2020

46

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1 January 2020

1

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1 January 2020

200-208

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1 January 2020

Strategies for retargeted gene delivery using vectors derived from lentiviruses.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

21 January 2018

Hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of reproduction by Polycomb Group complexes in animals and plants.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of polycomb group proteins in stem cell self-renewal and cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Unlocking the potential of the human genome with RNA interference

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

RNA interference-based gene silencing in mice: the development of a novel therapeutical strategy

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Approaches for chemically synthesized siRNA and vector-mediated RNAi

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Microarrays of lentiviruses for gene function screens in immortalized and primary cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

A phase I/II clinical trial of beta-globin gene therapy for beta-thalassemia

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of an interferon response by RNAi vectors in mammalian cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Knockdown by RNAi-proceed with caution

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthetic shRNAs as potent RNAi triggers.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

WWOX gene restoration prevents lung cancer growth in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural intermediates in microtubule assembly and disassembly: how and why?

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of stathmin in the regulation of the cell cycle

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteomic analysis of hepatitis B virus-associated hepatocellular carcinoma: Identification of potential tumor markers.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Stathmin overexpression cooperates with p53 mutation and osteopontin overexpression, and is associated with tumour progression, early recurrence, and poor prognosis in hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-mediated negative regulation of stathmin/Op18 expression is associated with G(2)/M cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin

1 reference

https://api.crossref.org/works/10.1002%2FHEP.21668

7 January 2021

based on heuristic

inferred from DOI database lookup

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