(Q42093812)

16 October 2017

CRISPR-Cas9 genome editing of a single regulatory element nearly abolishes target gene expression in mice--brief report (English)

1 reference

16 October 2017

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Yu Han

1

1 reference

16 October 2017

Orazio J Slivano

2

1 reference

16 October 2017

Christine K Christie

3

1 reference

16 October 2017

Albert W Cheng

4

1 reference

16 October 2017

Joseph M Miano

5

1 reference

16 October 2017

language of work or name

English

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publication date

23 December 2014

1 reference

Arteriosclerosis, Thrombosis, and Vascular Biology

16 October 2017

1 reference

16 October 2017

35

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16 October 2017

2

1 reference

16 October 2017

312-315

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CRISPR-Cas systems for editing, regulating and targeting genomes

16 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Fine tuning of craniofacial morphology by distant-acting enhancers

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Regulation of 130-kDa smooth muscle myosin light chain kinase expression by an intronic CArG element.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Efficient genome editing in zebrafish using a CRISPR-Cas system

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Multiplex genome engineering using CRISPR/Cas systems

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Systematic localization of common disease-associated variation in regulatory DNA

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Lost in transgenesis: a user's guide for genetically manipulating the mouse in cardiac research

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Smooth muscle calponin: an unconventional CArG-dependent gene that antagonizes neointimal formation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Identifying functional single nucleotide polymorphisms in the human CArGome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Smooth muscle of telokin-deficient mice exhibits increased sensitivity to Ca2+ and decreased cGMP-induced relaxation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Suppression of cancer phenotypes through a multifunctional actin-binding protein, calponin, that attacks cancer cells and simultaneously protects the host from invasion

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Serum response factor: toggling between disparate programs of gene expression

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Size matters: use of YACs, BACs and PACs in transgenic animals

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Germ-line transformation of mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Effective gene targeting in rabbits using RNA-guided Cas9 nucleases.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304932

Serum response factor-dependent regulation of the smooth muscle calponin gene

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25538209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1161/ATVBAHA.114.305017

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

25538209

1 reference