(Q42109502)

16 October 2017

Proteolytic generation of constitutive tyrosine kinase activity of the human insulin receptor (English)

1 reference

16 October 2017

1 reference

1 reference

2

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16 October 2017

Hsuan JJ

1

1 reference

16 October 2017

Clark S

series ordinal

3

1 reference

16 October 2017

Waterfield MD

series ordinal

4

1 reference

16 October 2017

language of work or name

English

0 references

publication date

1 April 1989

1 reference

16 October 2017

1 reference

16 October 2017

259

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16 October 2017

2

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16 October 2017

519-527

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Internalization and molecular processing of insulin receptors in isolated rat adipocytes

16 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Internalization and recycling of insulin receptors in hepatoma cells. Absence of regulation by receptor occupancy

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Rapid, reversible internalization of cell surface insulin receptors. Correlation with insulin-induced down-regulation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

A mutation at the ATP-binding site of pp60v-src abolishes kinase activity, transformation, and tumorigenicity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Antibody-induced down-regulation of a mutated insulin receptor lacking an intact cytoplasmic domain

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

The insulin receptor. Structural basis for high affinity ligand binding

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Activation of transforming potential of the human insulin receptor gene

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Internalization of insulin receptors and HLA antigens in human hepatoma cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Internalization of functional epidermal growth factor:receptor/kinase complexes in A-431 cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

A membrane-anchored cytoplasmic domain of the human insulin receptor mediates a constitutively elevated insulin-independent uptake of 2-deoxyglucose.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Insulin-mimetic effect of trypsin on the insulin receptor tyrosine kinase in intact adipocytes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-src

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

The erbB gene of avian erythroblastosis virus is a member of the src gene family

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Defective internalization of insulin and its receptor in cells expressing mutated insulin receptors lacking kinase activity

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138539

Release from Density Dependent Growth Inhibition by Proteolytic Enzymes

17 August 2018

1 reference

12 December 2020

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin

1 reference

12 December 2020

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes

1 reference

12 December 2020

Purification of the insulin receptor from human placenta by chromatography on immobilized wheat germ lectin and receptor antibody

1 reference

12 December 2020

Unimpaired signal transduction by the adipocyte insulin receptor following its partial proteolytic fragmentation

1 reference

12 December 2020

Independent control of selected insulin-sensitive cell membrane and intracellular functions-the linkage of cell membrane and intracellular events controlled by insulin. III. The influence of trypsin on cell membrane hexose transport and on glycogen

1 reference

12 December 2020

Ligand-induced translocation of insulin receptors in intact rat liver

1 reference

12 December 2020

The insulin receptor protein kinase. Physicochemical requirements for activity

1 reference

12 December 2020

Insulin-like effect of trypsin on the phosphorylation of rat adipocyte insulin receptor

1 reference

12 December 2020

Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell

1 reference

12 December 2020

Identification of insulin receptor tyrosine residues autophosphorylated in vitro

1 reference

12 December 2020

Separate domains of the insulin receptor contain sites of autophosphorylation and tyrosine kinase activity

1 reference

12 December 2020

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1 reference

12 December 2020

Insulin-dependent intermolecular subunit communication between isolated alpha beta heterodimeric insulin receptor complexes

1 reference

12 December 2020

Tryptic activation of the insulin receptor. Proteolytic truncation of the alpha-subunit releases the beta-subunit from inhibitory control

1 reference

12 December 2020

A radioimmunoassay for human epidermal growth factor receptor

1 reference

12 December 2020

Insulin receptors on Chinese hamster ovary (CHO) cells: altered insulin binding to glycosylation mutants

1 reference

12 December 2020

Dithiothreitol activation of the insulin receptor/kinase does not involve subunit dissociation of the native alpha 2 beta 2 insulin receptor subunit complex

1 reference

12 December 2020

Initiation of chick cell division by trypsin action at the cell surface

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2590519

1 reference

release_yrta7ihuczbznoejpxuzzaqqse

16 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yrta7ihuczbznoejpxuzzaqqse

24 November 2022

mapped directly with Wikidata item

1 reference

16 October 2017

PubMed publication ID

2719663

1 reference