(Q42117260)

English

Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2

scientific article published on 10 August 2009

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scholarly article

1 reference

Europe PubMed Central

16 October 2017

Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2 (English)

1 reference

Europe PubMed Central

16 October 2017

2

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Europe PubMed Central

16 October 2017

author name string

Nadya Dimitrova

1

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Europe PubMed Central

16 October 2017

language of work or name

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publication date

10 August 2009

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Europe PubMed Central

16 October 2017

Molecular and Cellular Biology

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Europe PubMed Central

16 October 2017

29

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Europe PubMed Central

16 October 2017

5552-5563

1 reference

Europe PubMed Central

16 October 2017

20

1 reference

Europe PubMed Central

16 October 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2756883/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Regulatory ubiquitylation in response to DNA double-strand breaks

1 reference

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MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

1 reference

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53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

1 reference

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Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

1 reference

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Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation

1 reference

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1 reference

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Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2

1 reference

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Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination

1 reference

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Human CtIP promotes DNA end resection

1 reference

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MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control

1 reference

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Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres

1 reference

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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.

1 reference

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MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres

2 references

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1 reference

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Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres

1 reference

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1 reference

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Interplay between human DNA repair proteins at a unique double-strand break in vivo

1 reference

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29 May 2018

The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres

1 reference

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29 May 2018

The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

1 reference

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29 May 2018

Functional human telomeres are recognized as DNA damage in G2 of the cell cycle

1 reference

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Shelterin: the protein complex that shapes and safeguards human telomeres

1 reference

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29 May 2018

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

1 reference

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29 May 2018

Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

1 reference

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29 May 2018

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

1 reference

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Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

1 reference

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Control of sister chromatid recombination by histone H2AX.

1 reference

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Telomere instability in a human tumor cell line expressing NBS1 with mutations at sites phosphorylated by ATM.

1 reference

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29 May 2018

DNA damage foci at dysfunctional telomeres

1 reference

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

1 reference

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29 May 2018

A new connection at human telomeres: association of the Mre11 complex with TRF2.

1 reference

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DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

1 reference

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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

1 reference

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1 reference

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Genomic instability in mice lacking histone H2AX

1 reference

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29 May 2018

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1 reference

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1 reference

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29 May 2018

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

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29 May 2018

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways

1 reference

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29 May 2018

Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.

1 reference

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29 May 2018

DNA damage-dependent nuclear dynamics of the Mre11 complex

1 reference

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NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

1 reference

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29 May 2018

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

1 reference

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29 May 2018

Mammalian telomeres end in a large duplex loop

1 reference

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TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

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Control of telomere length by the human telomeric protein TRF1

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

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H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

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17 August 2018

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17 August 2018

The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.

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Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

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1 December 2018

The cellular response to DNA double-strand breaks: defining the sensors and mediators

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00476-09

1 reference

Europe PubMed Central

16 October 2017

1 reference

Europe PubMed Central

16 October 2017

1 reference

Europe PubMed Central

16 October 2017

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