(Q42131334)

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A molecular description of ligand binding to the two overlapping binding pockets of the nuclear vitamin D receptor (VDR): structure-function implications

scientific article published on 14 April 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

A molecular description of ligand binding to the two overlapping binding pockets of the nuclear vitamin D receptor (VDR): structure-function implications (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

0 references

1 reference

based on heuristic

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1 reference

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author name string

Mathew T Mizwicki

1

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Danusa Menegaz

2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Sepideh Yaghmaei

3

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Helen L Henry

4

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Anthony W Norman

5

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Europe PubMed Central

PMC publication ID

17 October 2017

publication date

14 April 2010

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Europe PubMed Central

PMC publication ID

17 October 2017

The Journal of Steroid Biochemistry and Molecular Biology

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Europe PubMed Central

PMC publication ID

17 October 2017

121

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Europe PubMed Central

PMC publication ID

17 October 2017

1-2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

98-105

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

On the mechanism underlying (23S)-25-dehydro-1alpha(OH)-vitamin D3-26,23-lactone antagonism of hVDRwt gene activation and its switch to a superagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Biologically active noncalcemic analogs of 1alpha,25-dihydroxyvitamin D with an abbreviated side chain containing no hydroxyl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Antagonistic Actions in Vivo of (23S)-25-Dehydro-1alpha-Hydroxyvitamin D(3-)26,23-Lactone on Calcium Metabolism Induced by 1alpha,25-Dihydroxyvitamin D(3).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Nonnuclear effects of the steroid hormone 1 alpha,25(OH)2-vitamin D3: analogs are able to functionally differentiate between nuclear and membrane receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Structure-function relationships in the vitamin D endocrine system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Biological activity assessment of 1α,25-dihydroxyvitamin D3-26,23-lactone in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Structural requirements for the interaction of 1 alpha, 25-(OH) 2- vitiamin D3 with its chick interestinal receptor system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Vitamin D and its analogs. VII. Solution conformations of vitamin D3 and 1.alpha.,25-dihydroxyvitamin D3 by high-resolution proton magnetic resonance spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Studies on vitamin D and its analogs. VIII. 3-deoxy-1α,25-dihydroxyvitamin D3, a potent new analog of 1α,25-(OH)2-D3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

29 May 2018

Inhibition of NFkappaB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

17 August 2018

1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

17 August 2018

A perspective on how the Vitamin D sterol/Vitamin D receptor (VDR) conformational ensemble model can potentially be used to understand the structure-function results of A-ring modified Vitamin D sterols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

17 August 2018

Applications of the Vitamin D sterol-Vitamin D receptor (VDR) conformational ensemble model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

17 August 2018

Mechanism and function of high vitamin D receptor levels in genetic hypercalciuric stone-forming rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

17 August 2018

1alpha,25-dihydroxyvitamin D(3)-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921884

17 August 2018

Enhanced biological activity of 1alpha,25-dihydroxy-20-epi-vitamin D3, the C-20 epimer of 1alpha,25-dihydroxyvitamin D3, is in part due to its metabolism into stable intermediary metabolites with significant biological activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20398762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3 an analog of 1alpha,25-(OH)2-D3, the active form of vitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/20398762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformation−Function Relationship of Vitamin D: Conformational Analysis Predicts Potential Side-Chain Structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20398762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JSBMB.2010.04.005

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

0 references

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