(Q42136608)

17 October 2017

Population of nonnative states of lysozyme variants drives amyloid fibril formation (English)

1 reference

17 October 2017

1

1 reference

17 October 2017

9

1 reference

17 October 2017

10

Christopher M Dobson

1 reference

17 October 2017

Maria F Mossuto

3

0 references

Nunilo Cremades

object named as

Nunilo Cremades

series ordinal

4

0 references

Tuomas Knowles

series ordinal

8

object named as

Tuomas P J Knowles

1 reference

17 October 2017

2

Anne Dhulesia

1 reference

17 October 2017

5

Janet R Kumita

1 reference

17 October 2017

Mireille Dumoulin

6

1 reference

17 October 2017

Mark E Welland

series ordinal

7

1 reference

17 October 2017

language of work or name

English

0 references

publication date

29 April 2011

1 reference

Journal of the American Chemical Society

17 October 2017

1 reference

17 October 2017

133

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17 October 2017

20

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17 October 2017

7737-7743

1 reference

The non-core regions of human lysozyme amyloid fibrils influence cytotoxicity

17 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

A non-natural variant of human lysozyme (I59T) mimics the in vitro behaviour of the I56T variant that is responsible for a form of familial amyloidosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

An analytical solution to the kinetics of breakable filament assembly

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Glimpses of the molecular mechanisms of beta2-microglobulin fibril formation in vitro: aggregation on a complex energy landscape

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Conformational properties of the aggregation precursor state of HypF-N.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Quartz crystal microbalance studies of multilayer glucagon fibrillation at the solid-liquid interface

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Identification of the core structure of lysozyme amyloid fibrils by proteolysis.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

The importance of sequence diversity in the aggregation and evolution of proteins

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

FT-IR approaches on amyloid fibril structure

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Techniques to study amyloid fibril formation in vitro

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Tuning the free-energy landscape of a WW domain by temperature, mutation, and truncation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Mutational analysis of the propensity for amyloid formation by a globular protein

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

"New view" of protein folding reconciled with the old through multiple unfolding simulations.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Human lysozyme gene mutations cause hereditary systemic amyloidosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Measurement of the individual pKa values of acidic residues of hen and turkey lysozymes by two-dimensional 1H NMR.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Navigating the folding routes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Surface attachment of protein fibrils via covalent modification strategies

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

The unfolded state of the murine prion protein and properties of single-point mutants related to human prion diseases

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Unfolded-state structure and dynamics influence the fibril formation of human prion protein

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Position-dependent electrostatic protection against protein aggregation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Structure and dynamics of a partially folded protein are decoupled from its mechanism of aggregation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Conformational stability of amyloid fibrils of beta2-microglobulin probed by guanidine-hydrochloride-induced unfolding

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Relationship between stability of folding intermediates and amyloid formation for the yeast prion Ure2p: a quantitative analysis of the effects of pH and buffer system

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Amyloid fibril formation and seeding by wild-type human lysozyme and its disease-related mutational variants.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Frequency Factors in a Landscape Model of Filamentous Protein Aggregation

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Protein Aggregation in Crowded Environments

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Local cooperativity in the unfolding of an amyloidogenic variant of human lysozyme

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

Formation and seeding of amyloid fibrils from wild-type hen lysozyme and a peptide fragment from the β-domain

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982536

The stability and folding process of amyloidogenic mutant human lysozymes

1 December 2018

1 reference

12 December 2020

Local cooperativity in an amyloidogenic state of human lysozyme observed at atomic resolution

1 reference

12 December 2020

Analysis of the acid-base titration curve of hen lysozyme

1 reference

12 December 2020

Effect of salt concentration on the pKa of acidic residues in lysozyme

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA109620D

1 reference

17 October 2017

1 reference

17 October 2017

PubMed publication ID

21528861

1 reference