(Q42141300)

English

Toll-like receptor 4 signaling leads to severe fungal infection associated with enhanced proinflammatory immunity and impaired expansion of regulatory T cells.

scientific article published on 14 December 2009

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008536%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Toll-like receptor 4 signaling leads to severe fungal infection associated with enhanced proinflammatory immunity and impaired expansion of regulatory T cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008536%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

toll-like receptor

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Flávio V. Loures

1

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15 January 2020

Maíra Felonato

3

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15 January 2020

5

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15 January 2020

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Adriana Pina

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15 January 2020

Vera L G Calich

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Vera L G Calich

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15 January 2020

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Eliseu F Araújo

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15 January 2020

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14 December 2009

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15 January 2020

Infection and Immunity

1 reference

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15 January 2020

78

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15 January 2020

3

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15 January 2020

1078-1088

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008536%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Modulation of adaptive immunity with Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Reciprocal regulation of IL-23 and IL-12 following co-activation of Dectin-1 and TLR signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Modulation of Toll-like receptor 2 (TLR2) and TLR4 responses by Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

A novel IL-17-dependent mechanism of cross protection: respiratory infection with mycoplasma protects against a secondary listeria infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Pivotal Advance: Toll-like receptor regulation of scavenger receptor-A-mediated phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Innate immunity to Paracoccidioides brasiliensis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Lipopolysaccharides from Bordetella pertussis and Bordetella parapertussis differently modulate human dendritic cell functions resulting in divergent prevalence of Th17-polarized responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Toll-like receptors and fungal infections: the role of TLR2, TLR4 and MyD88 in paracoccidioidomycosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Toll-like receptor 4 plays a role in macrophage phagocytosis during peritoneal sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Signalling and phagocytosis in the orchestration of host defence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Importance of complement 3 and mannose receptors in phagocytosis of Paracoccidioides brasiliensis conidia by Nramp1 congenic macrophages lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Natural regulatory T cells in infectious disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Involvement of CD14, toll-like receptors 2 and 4, and MyD88 in the host response to the fungal pathogen Cryptococcus neoformans in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Activation of dendritic cells: translating innate into adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Immunity to fungal infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Induced humoral immunity and vaccination against major human fungal pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Cytokines and lymphocyte proliferation in juvenile and adult forms of paracoccidioidomycosis: comparison with infected and non-infected controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Endocytosis and signaling. an inseparable partnership

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Endocytosis and signaling cascades: a close encounter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Pulmonary paracoccidioidomycosis in resistant and susceptible mice: relationship among progression of infection, bronchoalveolar cell activation, cellular immune response, and specific isotype patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Cell Wall Composition of the Yeast and Mycelial Forms of Paracoccidioides brasiliensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

Host-parasite relationships in paracoccidioidomycosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

The activation of the complement system by Paracoccidioides brasiliensis in vitro: Its opsonic effect and possible significance for an in vivo model of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

29 May 2018

TLR-2, TLR-4 and dectin-1 expression in human monocytes and neutrophils stimulated by Paracoccidioides brasiliensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

IL-17/Th17 in anti-fungal immunity: what's new?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Stimulation of dendritic cells via the dectin-1/Syk pathway allows priming of cytotoxic T-cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Alveolar macrophages from susceptible mice are more competent than those of resistant mice to control initial Paracoccidioides brasiliensis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Cryptococcus neoformans capsular glucuronoxylomannan induces expression of fas ligand in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

MyD88 and TLR2, but not TLR4, are required for host defense against Cryptococcus neoformans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Toll-dependent control mechanisms of CD4 T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Regulation of phagosome maturation by signals from toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Identification of a TLR4- and TRIF-dependent activation program of dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

GP43 from Paracoccidioides brasiliensis inhibits macrophage functions. An evasion mechanism of the fungus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Resistance to Paracoccidioides brasiliensis infection is linked to a preferential Th1 immune response, whereas susceptibility is associated with absence of IFN-gamma production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

17 August 2018

Interaction betweenParacoccidioides brasiliensisand Pulmonary Dendritic Cells Induces Interleukin‐10 Production and Toll‐Like Receptor–2 Expression: Possible Mechanisms of Susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

1 December 2018

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825906

1 December 2018

IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of Toll IL-1R8 Exacerbates Th17 Cell Responses in Fungal Infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MyD88 is dispensable for resistance to Paracoccidioides brasiliensis in a murine model of blood-borne disseminated infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR2 is a negative regulator of Th17 cells and tissue pathology in a pulmonary model of fungal infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 and neutralization of endogenous IL-10 revert the in vitro antigen-specific cellular immunosuppression of paracoccidioidomycosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saccharomyces cerevisiae- and Candida albicans-derived mannan induced production of tumor necrosis factor alpha by human monocytes in a CD14- and Toll-like receptor 4-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida albicans phospholipomannan is sensed through toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor (TLR) 2 and TLR4 are essential for Aspergillus-induced activation of murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The source of the growth-promoting factor(s) affects the plating efficiency of Paracoccidioides brasiliensis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycolipids from Paracoccidioides brasiliensis. Isolation of a galactofuranose-containing glycolipid reactive with sera of patients with paracoccidioidomycosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T(H)-17: a giant step from T(H)1 and T(H)2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flow-cytometric analysis of cytokine production in human paracoccidioidomycosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of fungal pathogens by toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.01198-09

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008536%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008536%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008536%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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