(Q42142167)

English

Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes

scientific article published on 21 September 2011

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scholarly article

1 reference

Europe PubMed Central

17 October 2017

Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes (English)

1 reference

Europe PubMed Central

17 October 2017

author name string

Takumi Satoh

1

1 reference

Europe PubMed Central

17 October 2017

Tayebeh Rezaie

2

1 reference

Europe PubMed Central

17 October 2017

Masaaki Seki

3

1 reference

Europe PubMed Central

17 October 2017

Carmen R Sunico

4

1 reference

Europe PubMed Central

17 October 2017

Takahito Tabuchi

5

1 reference

Europe PubMed Central

17 October 2017

Tomomi Kitagawa

6

1 reference

Europe PubMed Central

17 October 2017

Mika Yanagitai

7

1 reference

Europe PubMed Central

17 October 2017

Mutsumi Senzaki

8

1 reference

Europe PubMed Central

17 October 2017

Chihiro Kosegawa

9

1 reference

Europe PubMed Central

17 October 2017

Hideharu Taira

10

1 reference

Europe PubMed Central

17 October 2017

Scott R McKercher

11

1 reference

Europe PubMed Central

17 October 2017

Jennifer K Hoffman

12

1 reference

Europe PubMed Central

17 October 2017

Gregory P Roth

13

1 reference

Europe PubMed Central

17 October 2017

Stuart A Lipton

14

1 reference

Europe PubMed Central

17 October 2017

language of work or name

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publication date

21 September 2011

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Europe PubMed Central

17 October 2017

Journal of Neurochemistry

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Europe PubMed Central

17 October 2017

119

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Europe PubMed Central

17 October 2017

3

1 reference

Europe PubMed Central

17 October 2017

569-578

1 reference

Europe PubMed Central

17 October 2017

The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO)

1 reference

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Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones

1 reference

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Signaling actions of electrophiles: anti-inflammatory therapeutic candidates

1 reference

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Heat shock transcription factor 1 inhibits expression of IL-6 through activating transcription factor 3.

1 reference

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Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells

1 reference

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Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.

1 reference

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The Nrf2-ARE cytoprotective pathway in astrocytes

1 reference

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Curcumin protects retinal cells from light-and oxidant stress-induced cell death

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Simple ortho- and para-hydroquinones as compounds neuroprotective against oxidative stress in a manner associated with specific transcriptional activation

1 reference

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Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione.

1 reference

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Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones

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Programmed cell death mechanisms in neurological disease

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29 May 2018

Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners

1 reference

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Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

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S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease

1 reference

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29 May 2018

Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.

1 reference

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29 May 2018

Pathologically activated therapeutics for neuroprotection

1 reference

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Sulfiredoxin, the cysteine sulfinic acid reductase specific to 2-Cys peroxiredoxin: its discovery, mechanism of action, and biological significance

1 reference

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Redox regulation of neuronal survival mediated by electrophilic compounds

1 reference

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Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses

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Cell signaling and neuronal death

1 reference

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Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer

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Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers

1 reference

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Oxidative stress in ARPE-19 cultures: do melanosomes confer cytoprotection?

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A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

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Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models

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1 reference

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1 reference

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1 reference

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17 August 2018

Identifiers

10.1111/J.1471-4159.2011.07449.X

1 reference

Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

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