(Q42146138)

17 October 2017

Overexpression of mitochondrial Hsp70/Hsp75 in rat brain protects mitochondria, reduces oxidative stress, and protects from focal ischemia (English)

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17 October 2017

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Lijun Xu

1

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17 October 2017

Ludmila A Voloboueva

2

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17 October 2017

YiBing Ouyang

3

1 reference

17 October 2017

John F Emery

4

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17 October 2017

Rona G Giffard

5

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17 October 2017

5 November 2008

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Journal of Cerebral Blood Flow & Metabolism

17 October 2017

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17 October 2017

29

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17 October 2017

2

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17 October 2017

365-374

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describes a project that uses

17 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3676940/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Bioenergetics of cerebral ischemia: a cellular perspective

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Mechanisms of impaired mitochondrial energy metabolism in acute and chronic neurodegenerative disorders

29 May 2018

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PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

29 May 2018

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The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases

29 May 2018

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Inhibition of mitochondrial function in astrocytes: implications for neuroprotection.

29 May 2018

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The role of poly(ADP-ribose) polymerase-1 in CNS disease

29 May 2018

1 reference

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Mitochondrial ROS-induced ROS release: an update and review

29 May 2018

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Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion

29 May 2018

1 reference

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Mitochondria and ischemia/reperfusion injury

29 May 2018

1 reference

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Oxidative stress and neuronal death/survival signaling in cerebral ischemia

29 May 2018

1 reference

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Mediation of cell death by poly(ADP-ribose) polymerase-1.

29 May 2018

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Astrocytic contributions to bioenergetics of cerebral ischemia

29 May 2018

1 reference

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Protection against ischemic brain injury by inhibition of mitochondrial oxidative stress

29 May 2018

1 reference

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Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice

29 May 2018

1 reference

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Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection

29 May 2018

1 reference

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Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis

29 May 2018

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Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74

29 May 2018

1 reference

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Implication of PBP74/mortalin/GRP75 in the radio-adaptive response

29 May 2018

1 reference

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Nitric oxide, mitochondria, and cell death

29 May 2018

1 reference

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The glucose-regulated proteins: stress induction and clinical applications

29 May 2018

1 reference

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Reactive oxygen radicals in signaling and damage in the ischemic brain

29 May 2018

1 reference

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Neuronal apoptosis after CNS injury: the roles of glutamate and calcium.

29 May 2018

1 reference

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Mitochondrial participation in ischemic and traumatic neural cell death

29 May 2018

1 reference

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Diffusion- and perfusion-weighted MR imaging of transient focal cerebral ischaemia in mice

29 May 2018

1 reference

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Mechanisms of protein translocation into mitochondria

29 May 2018

1 reference

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Secondary bioenergetic failure after transient focal ischaemia is due to mitochondrial injury.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Functional binding of cardiolipin to cytochrome c oxidase

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Cloning and subcellular localization of human mitochondrial hsp70

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Capacity for substrate utilization in oxidative metabolism by neurons, astrocytes, and oligodendrocytes from developing brain in primary culture

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Free radicals and brain damage.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Middle cerebral artery occlusion in rats: a neurological and pathological evaluation of a reproducible model

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Mitochondria protection from hypoxia/reoxygenation injury with mitochondria heat shock protein 70 overexpression

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Mitochondrial NAD+-linked State 3 respiration and complex-I activity are compromised in the cerebral cortex of 3-nitropropionic acid-induced rat model of Huntington's disease.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Aminoguanidine inhibits caspase-3 and calpain activation without affecting microglial activation following neonatal transient cerebral ischemia

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

The carboxyl-terminal domain of inducible Hsp70 protects from ischemic injury in vivo and in vitro

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Effect of GRP75/mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

NAD+ as a metabolic link between DNA damage and cell death.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Ischemic cell death: dynamics of delayed secondary energy failure during reperfusion following focal ischemia

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Astrocyte energetics, function, and death under conditions of incomplete ischemia: a mechanism of glial death in the penumbra.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Ischemia-induced death of astrocytes and neurons in primary culture: pitfalls in quantifying neuronal cell death

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

Cloning of rat grp75, an hsp70‐family member, and its expression in normal and ischemic brain

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676940

The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine heart submitochondrial particles

17 August 2018

1 reference

12 December 2020

Evolution of brain infarction after transient focal cerebral ischemia in mice

1 reference

12 December 2020

A subset of newly synthesized polypeptides in mitochondria from human endothelial cells exposed to hydroperoxide stress

1 reference

12 December 2020

Proteome Analysis and Functional Expression Identify Mortalin as an Antiapoptotic Gene Induced by Elevation of [Na + ] i /[K + ] i Ratio in Cultured Vascular Smooth Muscle Cells

1 reference

12 December 2020

Trolox protects mitochondrial complex IV from nitric oxide-mediated damage in astrocytes

1 reference

12 December 2020

Local hemodynamic changes during transient middle cerebral artery occlusion and recirculation in the rat: a [14C]iodoantipyrine autoradiographic study

1 reference

12 December 2020

Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport

1 reference

12 December 2020

p75, a member of the heat shock protein family, undergoes tyrosine phosphorylation in response to oxidative stress

1 reference

12 December 2020

Activity of mitochondrial respiratory chain enzymes after transient focal ischemia in the rat

1 reference

12 December 2020

Nitric-oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome C release

1 reference

12 December 2020

Identifiers

DOI

10.1038/JCBFM.2008.125

1 reference

17 October 2017

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17 October 2017

PubMed publication ID

18985056

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