(Q42162230)

17 October 2017

title

Concerted regulation of inhibitory activity of alpha 1-antitrypsin by the native strain distributed throughout the molecule (English)

1 reference

17 October 2017

Eun Joo Seo

1

1 reference

17 October 2017

Cheolju Lee

series ordinal

2

1 reference

17 October 2017

Myeong-Hee Yu

series ordinal

3

1 reference

17 October 2017

language of work or name

English

0 references

publication date

7 February 2002

1 reference

Journal of Biological Chemistry

17 October 2017

published in

1 reference

17 October 2017

volume

277

1 reference

17 October 2017

issue

16

1 reference

17 October 2017

page(s)

14216-14220

1 reference

Principles that govern the folding of protein chains

17 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

A spring-loaded mechanism for the conformational change of influenza hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Core structure of gp41 from the HIV envelope glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Regulation of Drosophila heat shock factor trimerization: global sequence requirements and independence of nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

What do dysfunctional serpins tell us about molecular mobility and disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Hormone binding globulins undergo serpin conformational change in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Structural basis for serpin inhibitor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Regulation of protein function by native metastability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

A 2.1 A resolution structure of an uncleaved alpha(1)-antitrypsin shows variability of the reactive center and other loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Cavities of alpha(1)-antitrypsin that play structural and functional roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Role of Lys335 in the metastability and function of inhibitory serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Effects of mutations in the hinge region of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Divining the serpin inhibition mechanism: a suicide substrate 'springe'?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

The structural puzzle of how serpin serine proteinase inhibitors work

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Probing the native strain iin alpha1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Metastability in the inhibitory mechanism of human alpha1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Distribution of the native strain in human alpha 1-antitrypsin and its association with protease inhibitor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Conversion of alpha 1-antichymotrypsin into a human neutrophil elastase inhibitor: demonstration of variants with different association rate constants, stoichiometries of inhibition, and complex stabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Distortion of the active site of chymotrypsin complexed with a serpin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

Folding pathway of human alpha 1-antitrypsin: characterization of an intermediate that is active but prone to aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110272200

21 January 2018

Identifiers

DOI

10.1074/JBC.M110272200

1 reference

17 October 2017

1 reference