(Q42169186)

17 October 2017

title

Synthesis of cidofovir and (S)-HPMPA ether lipid prodrugs (English)

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17 October 2017

James R Beadle

1

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17 October 2017

publication date

1 June 2007

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Current protocols in nucleic acid chemistry / editorial board, Serge L. Beaucage ... [et al.]

17 October 2017

published in

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17 October 2017

volume

Chapter 15

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17 October 2017

page(s)

Unit 15.2

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Increased antiviral activity of 1-O-hexadecyloxypropyl-[2-(14)C]cidofovir in MRC-5 human lung fibroblasts is explained by unique cellular uptake and metabolism.

17 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Cidofovir protects mice against lethal aerosol or intranasal cowpox virus challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Acyclic nucleoside phosphonates: a key class of antiviral drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

A novel selective broad-spectrum anti-DNA virus agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Phosphonomethoxyalkyl Analogs of Nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Antiviral acyclic nucleoside phosphonates structure activity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Antiviral activities of oral 1-O-hexadecylpropanediol-3-phosphoacyclovir and acyclovir in woodchucks with chronic woodchuck hepatitis virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Alkoxyalkyl esters of (S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine are potent inhibitors of the replication of wild-type and drug-resistant human immunodeficiency virus type 1 in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

An efficient process for the synthesis of cyclic HPMPC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Application of the cycloSal-prodrug approach for improving the biological potential of phosphorylated biomolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Design and development of oral drugs for the prophylaxis and treatment of smallpox infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cidofovir against human and murine cytomegalovirus replication in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1502S29

10.1002/0471142700.NC1502S29

21 January 2018

Identifiers

DOI

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17 October 2017

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