(Q42214018)

18 October 2017

Loss of p16(Ink4a) function rescues cellular senescence induced by telomere dysfunction (English)

1 reference

18 October 2017

1 reference

Xiufeng Zhang

1

1 reference

18 October 2017

Xiaoming Wu

series ordinal

2

1 reference

18 October 2017

Wenru Tang

series ordinal

3

1 reference

18 October 2017

Ying Luo

series ordinal

4

1 reference

18 October 2017

language of work or name

English

0 references

publication date

16 May 2012

1 reference

International Journal of Molecular Sciences

18 October 2017

1 reference

18 October 2017

13

1 reference

18 October 2017

5

1 reference

18 October 2017

5866-5877

1 reference

Creative Commons Attribution 4.0 International

18 October 2017

start time

16 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Aging or tumor: the crosstalk between telomerase and p53

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Telomere dysfunction in human keratinocytes elicits senescence and a novel transcription profile

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Telomeres: cancer to human aging

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

p16INK4a as a second effector of the telomere damage pathway

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Shelterin: the protein complex that shapes and safeguards human telomeres

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Essential role of limiting telomeres in the pathogenesis of Werner syndrome

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Different telomere damage signaling pathways in human and mouse cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Protection of mammalian telomeres

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Mice without telomerase: what can they teach us about human cancer?

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

The Werner syndrome protein is a DNA helicase

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382785

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

26 October 2017

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FIJMS13055866

Significant Role for p16INK4a in p53-Independent Telomere-Directed Senescence

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FIJMS13055866

Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22754337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22754337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Telomere positional effects and the regulation of cellular senescence

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22754337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJMS13055866

1 reference

18 October 2017

1 reference

18 October 2017

PubMed publication ID

22754337

1 reference