(Q42259826)

English

Lipopolysaccharide impairs amyloid β efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier

scientific article published on 29 June 2012

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22747709%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Lipopolysaccharide impairs amyloid β efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier (English)

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22747709%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

cerebrospinal fluid

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lipopolysaccharide

0 references

blood–brain barrier

1 reference

based on heuristic

inferred from title

Michelle A Erickson

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22747709%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Yoichi Morofuji

3

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6 February 2020

William A Banks

6

object named as

William A Banks

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6 February 2020

author name string

Pehr E Hartvigson

2

1 reference

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6 February 2020

Joshua B Owen

4

1 reference

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6 February 2020

D Allan Butterfield

5

1 reference

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6 February 2020

publication date

29 June 2012

1 reference

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6 February 2020

Journal of Neuroinflammation

1 reference

Europe PubMed Central

PMC publication ID

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6 February 2020

9

1 reference

Europe PubMed Central

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6 February 2020

150

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Europe PubMed Central

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6 February 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3410805/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation

1 reference

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Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide

1 reference

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Neuronal death induced by nanomolar amyloid β is mediated by primary phagocytosis of neurons by microglia

1 reference

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Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent

1 reference

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Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: multiplex quantification with path analysis.

1 reference

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Amyloid-β peptide(1-40) elimination from cerebrospinal fluid involves low-density lipoprotein receptor-related protein 1 at the blood-cerebrospinal fluid barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

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Restraint stress and repeated corticotrophin-releasing factor receptor activation in the amygdala both increase amyloid-β precursor protein and amyloid-β peptide but have divergent effects on brain-derived neurotrophic factor and pre-synaptic protei

1 reference

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Impact of p-glycoprotein inhibition and lipopolysaccharide administration on blood-brain barrier transport of colistin in mice

1 reference

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Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: implications for Aβ accumulation in AD brain

1 reference

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Low‐density lipoprotein receptor‐related protein‐1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β‐peptide elimination from the brain

1 reference

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Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay

1 reference

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Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease

1 reference

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1 reference

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CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.

1 reference

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26 October 2017

Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease

1 reference

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Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition

1 reference

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26 October 2017

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Lipopolysaccharide impairs blood-brain barrier P-glycoprotein function in mice through prostaglandin- and nitric oxide-independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Gamma-secretase limits the inflammatory response through the processing of LRP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid beta peptides in an in vitro model of the blood-brain barrier cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Molecular inflammation: underpinnings of aging and age-related diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

1 reference

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26 October 2017

Regulated intramembrane proteolysis of the low-density lipoprotein receptor-related protein mediates ischemic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Cerebral clearance of human amyloid-beta peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

The choroid plexus removes beta-amyloid from brain cerebrospinal fluid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Systemic catabolism of Alzheimer's Abeta40 and Abeta42.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

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Efflux of human and mouse amyloid β proteins 1–40 and 1–42 from brain: impairment in a mouse model of alzheimer's disease

1 reference

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THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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Phosphorylation of LRP1: regulation of transport and signal transduction

1 reference

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26 October 2017

Amyloid-beta: an antioxidant that becomes a pro-oxidant and critically contributes to Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

26 October 2017

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3410805

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Inflammation and Alzheimer's disease

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Relationship of senescence of cerebrospinal fluid circulatory system to dementias of the aged

1 reference

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Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

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Clearance and binding of two electrophoretic "fast" forms of human alpha 2-macroglobulin.

1 reference

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Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins

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Interleukin-1 stimulates the beta-amyloid precursor protein promoter

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1 reference

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2011 Alzheimer's disease facts and figures

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1 reference

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Impairments in brain-to-blood transport of amyloid-β and reabsorption of cerebrospinal fluid in an animal model of Alzheimer's disease are reversed by antisense directed against amyloid-β protein precursor.

1 reference

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ABC efflux transporters in brain vasculature of Alzheimer's subjects

1 reference

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LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

1 reference

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A physiological role for amyloid-beta protein:enhancement of learning and memory

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Involvement of the receptor for advanced glycation-end products (RAGE) in beta-amyloid-induced toxic effects in rat cerebromicrovascular endothelial cells cultured in vitro

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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17 August 2018

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1 reference

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17 August 2018

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

1 reference

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17 August 2018

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1 reference

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17 August 2018

Altered cytokine production in the elderly.

1 reference

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17 August 2018

Stopping a thief and killer: Alzheimer's disease crisis demands greater commitment to research.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-150

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Cultured human and canine endothelial cells from brain microvessels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22747709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major involvement of low-density lipoprotein receptor-related protein 1 in the clearance of plasma free amyloid beta-peptide by the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22747709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The critical component to establish in vitro BBB model: Pericyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/22747709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apical-to-basolateral transport of amyloid-β peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22747709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From the liver to the blood-brain barrier: an interconnected system regulating brain amyloid-β levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22747709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-9-150

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22747709%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1742-2094-9-150

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22747709%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22747709%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

ResearchGate publication ID

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