(Q42266105)

19 October 2017

Molecular dynamics study of water and Na+ ions in models of the pore region of the nicotinic acetylcholine receptor. (English)

1 reference

19 October 2017

G R Smith

1

1 reference

PMCID

1181036

19 October 2017

M S Sansom

series ordinal

2

1 reference

PMCID

1181036

19 October 2017

language of work or name

English

0 references

publication date

1 September 1997

1 reference

19 October 2017

1 reference

19 October 2017

73

1 reference

19 October 2017

3

1 reference

19 October 2017

1364-1381

1 reference

An information theory model of hydrophobic interactions

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9' position

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Solvation, water permeation, and ionic selectivity of a putative model for the pore region of the voltage-gated sodium channel.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Effects of mutating leucine to threonine in the M2 segment of alpha1 and beta1 subunits of GABAA alpha1beta1 receptors

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Water in channel-like cavities: structure and dynamics.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Molecular dynamics simulations of water within models of ion channels

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Nicotinic receptors in the development and modulation of CNS synapses.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Design of molecular function: channels of communication

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Ion transport in the gramicidin channel: molecular dynamics study of single and double occupancy

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Parallel helix bundles and ion channels: molecular modeling via simulated annealing and restrained molecular dynamics

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Beta-structure in the membrane-spanning part of the nicotinic acetylcholine receptor (or how helical are transmembrane helices?).

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Molecular Dynamics Simulations of the Gramicidin Channel

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

The pore dimensions of gramicidin A.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Stratification of the channel domain in neurotransmitter receptors

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

The permeability of the endplate channel to organic cations in frog muscle

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

The selectivity filter of a ligand-gated ion channel. The helix-M2 model of the ion channel of the nicotinic acetylcholine receptor

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

M2 delta, a candidate for the structure lining the ionic channel of the nicotinic cholinergic receptor

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

General continuum theory for multiion channel. I. Theory

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Nicotinic acetylcholine receptor superfamily of ligand-gated ion channels

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

The permeation pathway of neurotransmitter-gated ion channels

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

A novel method for structure-based prediction of ion channel conductance properties.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Projection structure of the nicotinic acetylcholine receptor: distinct conformations of the alpha subunits.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Temperature dependence of conductivity in electrolyte solutions and ionic channels of biological membranes.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

A mixed helix-beta-sheet model of the transmembrane region of the nicotinic acetylcholine receptor.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181036

Acetylcholine receptor channel imaged in the open state

17 August 2018

1 reference

12 December 2020

Structural features of isolated M2 helices of nicotinic receptors. Simulated annealing via molecular dynamics studies

1 reference

12 December 2020

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1 reference

12 December 2020

Water-mediated conformational transitions in nicotinic receptor M2 helix bundles: a molecular dynamics study.

1 reference

12 December 2020

Location of a threonine residue in the α -subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel

1 reference

12 December 2020

Kinked structures of isolated nicotinic receptor M2 helices: a molecular dynamics study

1 reference

12 December 2020

Pore size and negative charge as structural determinants of permeability in the Torpedo nicotinic acetylcholine receptor channel

1 reference

12 December 2020

Nicotinic acetylcholine receptor at 9 A resolution.

1 reference

12 December 2020

Modelling membrane proteins using structural restraints

1 reference

12 December 2020

Modelling packing interactions in parallel helix bundles: pentameric bundles of nicotinic receptor M2 helices

1 reference

12 December 2020

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H]chlorpromazine labels homologous residues in the beta and delta chains

1 reference

12 December 2020

10.1016/S0006-3495(97)78169-4

Identifiers

DOI

1 reference

19 October 2017

1 reference

19 October 2017

1 reference

PMCID

1181036