(Q42273053)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

10

1 reference

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12 February 2020

Markus M Lerch

18

1 reference

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12 February 2020

Julia Mayerle

2

1 reference

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12 February 2020

Miklós Sahin-Tóth

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Thomas Reinheckel

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Ali Aghdassi

14

1 reference

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12 February 2020

11

Matthias Sendler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

16

Steffen Teller

1 reference

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12 February 2020

15

Annegret Dummer

1 reference

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12 February 2020

17

Walter Halangk

1 reference

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12 February 2020

author name string

Thomas Wartmann

1

1 reference

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12 February 2020

Thilo Kähne

3

1 reference

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12 February 2020

Manuel Ruthenbürger

5

1 reference

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12 February 2020

Rainer Matthias

6

1 reference

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12 February 2020

Anne Kruse

7

1 reference

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12 February 2020

Christoph Peters

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Hans Lippert

12

1 reference

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12 February 2020

Hans-Ulrich Schulz

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

10 November 2009

1 reference

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12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

138

1 reference

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12 February 2020

issue

2

1 reference

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12 February 2020

page(s)

726-737

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.

12 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Cathepsin-regulated apoptosis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Association of cathepsin B gene polymorphisms with tropical calcific pancreatitis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: cathepsin B generates AA amyloid proteins and cathepsin L may prevent their formation.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

High-affinity Ca(2+) binding inhibits autoactivation of rat trypsinogen

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

The effect of chloroquine administration on two experimental models of acute pancreatitis.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Luminal endocytosis and intracellular targeting by acinar cells during early biliary pancreatitis in the opossum

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Crystal structure of bovine trypsinogen at 1-8 A resolution. I. Data collection, application of patterson search techniques and preliminary structural interpretation

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Cathepsin B gene polymorphism Val26 is not associated with idiopathic chronic pancreatitis in European patients

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Cell death in pancreatitis: caspases protect from necrotizing pancreatitis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Spontaneous and sporadic trypsinogen mutations in idiopathic pancreatitis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Trypsin activity is not involved in premature, intrapancreatic trypsinogen activation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941736

Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19900452

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cathepsin L--a lysosomal cysteine proteinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19900452

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The activation of trypsinogen by cathepsin B

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19900452

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1053/J.GASTRO.2009.10.048

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19900452%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19900452

1 reference