(Q42274395)

English

Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus

scientific article published on 18 April 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus (English)

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

0 references

reperfusion injury

1 reference

based on heuristic

inferred from title

cerebral infarction

1 reference

based on heuristic

inferred from title

author name string

Ketan Chu

1

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Bo Yin

2

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Jingye Wang

3

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Guoping Peng

4

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Hui Liang

5

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Ziqi Xu

6

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Yue Du

7

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Marong Fang

8

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Qiang Xia

9

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Benyan Luo

10

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

publication date

18 April 2012

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

69

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Astroglial P2X7 receptor current density increased following long-term exposure to rotenone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

The activation of P2X7 receptor induces cathepsin D-dependent production of a 20-kDa form of IL-1β under acidic extracellular pH in LPS-primed microglial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Combating innate inflammation: a new paradigm for acute treatment of stroke?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

P2X7 receptor regulates leukocyte infiltrations in rat frontoparietal cortex following status epilepticus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

The P2X7‐Egr pathway regulates nucleotide‐dependent inflammatory gene expression in microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Current and future recanalization strategies for acute ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

P2X7 receptor signaling pathway as a therapeutic target for neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

The P2X7 purinergic receptor: from physiology to neurological disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Inflammation and brain injury: acute cerebral ischaemia, peripheral and central inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Recent patents on novel P2X(7) receptor antagonists and their potential for reducing central nervous system inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Post-ischemic brain damage: pathophysiology and role of inflammatory mediators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

P2X7-related modulation of pathological nociception in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Morris water maze: procedures for assessing spatial and related forms of learning and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

A role for P2X7 in microglial proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

P2X7 receptors in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

The P2X7 receptor: a key player in IL-1 processing and release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Activation of P2X7 purinoceptor-stimulated TGF-β1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Molecular physiology of P2X receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Involvement of inflammatory cytokines in central nervous system injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Distribution of P2X receptors on astrocytes in juvenile rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Apparent species differences in the kinetic properties of P2X(7) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Delayed neuronal death in the gerbil hippocampus following ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Developments of a water-maze procedure for studying spatial learning in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

A new model of bilateral hemispheric ischemia in the unanesthetized rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

26 October 2017

Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

29 May 2018

P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

29 May 2018

P2X7 receptors mediate ischemic damage to oligodendrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

29 May 2018

Oral administration of grape polyphenol extract ameliorates cerebral ischemia/reperfusion-induced neuronal damage and behavioral deficits in gerbils: comparison of pre- and post-ischemic administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

29 May 2018

P2X7 receptor modulation on microglial cells and reduction of brain infarct caused by middle cerebral artery occlusion in rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

29 May 2018

Activation of P2 nucleotide receptors stimulates acid efflux from astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

29 May 2018

The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

Block of purinergic P2X(7) receptor is neuroprotective in an animal model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

Possible involvement of P2X7 receptor activation in microglial neuroprotection against focal cerebral ischemia in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

Role of P2X7 receptors in ischemic and excitotoxic brain injury in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

Effects of global ischemia duration on neuronal, astroglial, oligodendroglial, and microglial reactions in the vulnerable hippocampal CA1 subregion in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

Oxidised adenosine 5'-triphosphate, a P2X(7) antagonist, is toxic to rat cerebellar granule neurones in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

Pharmacological characterization of recombinant human and rat P2X receptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418181

17 August 2018

P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-69

21 January 2018

Severe global cerebral ischemia-induced programmed necrosis of hippocampal CA1 neurons in rat is prevented by 3-methyladenine: a widely used inhibitor of autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22513224

12 December 2020

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Identifiers

10.1186/1742-2094-9-69

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

ResearchGate publication ID

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