(Q42322397)

English

Synthesis and evaluation of eight- and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase 2, and other glycosidases

scientific article published on 20 March 2012

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Europe PubMed Central

PMC publication ID

26 October 2017

Synthesis and evaluation of eight- and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase 2, and other glycosidases (English)

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

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Gunda I Georg

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Europe PubMed Central

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26 October 2017

7

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Joseph S Tash

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Europe PubMed Central

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26 October 2017

author name string

Jae Chul Lee

1

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Europe PubMed Central

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26 October 2017

Subhashree Francis

2

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Europe PubMed Central

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26 October 2017

Dinah Dutta

3

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Europe PubMed Central

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26 October 2017

Vijayalaxmi Gupta

4

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Europe PubMed Central

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26 October 2017

Yan Yang

5

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Europe PubMed Central

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26 October 2017

Jin-Yi Zhu

6

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Europe PubMed Central

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26 October 2017

Ernst Schönbrunn

8

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26 October 2017

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publication date

20 March 2012

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Europe PubMed Central

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26 October 2017

Journal of Organic Chemistry

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Europe PubMed Central

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26 October 2017

77

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Europe PubMed Central

PMC publication ID

26 October 2017

7

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

3082-3098

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Identification of potent and selective glucosylceramide synthase inhibitors from a library of N-alkylated iminosugars

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Binding of 3,4,5,6-Tetrahydroxyazepanes to the Acid-β-glucosidase Active Site: Implications for Pharmacological Chaperone Design for Gaucher Disease

1 reference

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26 October 2017

Iminosugars as therapeutic agents: recent advances and promising trends

1 reference

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26 October 2017

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain

1 reference

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26 October 2017

Oral administration of a retinoic Acid receptor antagonist reversibly inhibits spermatogenesis in mice

1 reference

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26 October 2017

Therapeutic applications of iminosugars: current perspectives and future opportunities

1 reference

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26 October 2017

Methylthioinosine Phosphorylase from Pseudomonas aeruginosa . Structure and Annotation of a Novel Enzyme in Quorum Sensing

1 reference

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26 October 2017

Recent methodological advances in male hormonal contraception

1 reference

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26 October 2017

Iminosugars past, present and future: medicines for tomorrow

1 reference

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26 October 2017

Hormonal approaches to male contraception

1 reference

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26 October 2017

Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo

1 reference

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26 October 2017

Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors

1 reference

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26 October 2017

Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation

1 reference

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26 October 2017

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase

1 reference

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26 October 2017

In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Abortion in the United States: incidence and access to services, 2005.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

New perspectives in non-hormonal male contraception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat Sertoli cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Oral maintenance clinical trial with miglustat for type I Gaucher disease: switch from or combination with intravenous enzyme replacement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

C-Alkyl 5-membered ring imino sugars as new potent cytotoxic glucosylceramide synthase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Pharmacological enhancement of mutated alpha-glucosidase activity in fibroblasts from patients with Pompe disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Miglustat has no apparent effect on spermatogenesis in normal men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Disparities in Rates of Unintended Pregnancy In the United States, 1994 and 2001

1 reference

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26 October 2017

Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Therapeutic applications of imino sugars in lysosomal storage disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1).

1 reference

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26 October 2017

Low dose gossypol for male contraception

1 reference

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26 October 2017

Antifertility Actions of a-Chlorohydrin in the Male

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Biochemical and structural study on a S529V mutant acid α-glucosidase responsive to pharmacological chaperones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Molecular interaction of imino sugars with human alpha-galactosidase: Insight into the mechanism of complex formation and pharmacological chaperone action in Fabry disease

1 reference

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17 August 2018

From D-glucose to enantiomerically pure cycloctanoses. The glycosidase inhibitory capacity of medium-ring carbasugars.

1 reference

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17 August 2018

Biological properties of D- and L-1-deoxyazasugars

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Surprising bacterial nucleotidyltransferase selectivity in the conversion of carbaglucose-1-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Low-dose N-butyldeoxynojirimycin (OGT 918) for type I Gaucher disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts

1 reference

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17 August 2018

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.

1 reference

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17 August 2018

Advances in male contraception

1 reference

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30 September 2018

Convergent approach toward the synthesis of the stereoisomers of C-6 homologues of 1-deoxynojirimycin and their analogues: evaluation as specific glycosidase inhibitors

1 reference

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12 December 2020

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Inhibition of Glycosphingolipid Biosynthesis: Application to Lysosomal Storage Disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of (+)-mycalamide A

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

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Studies on the constituents of Broussonetia species. VII. Four new pyrrolidine alkaloids, broussonetines M, O, P, and Q, as inhibitors of glycosidase, from Broussonetia kazinoki SIEB

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

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Development of adamantan-1-yl-methoxy-functionalized 1-deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

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Inhibition of nonmammalian glycosidases by azetidine iminosugars derived from stable 3,5-di-O-triflates of pentoses

1 reference

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12 December 2020

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Accumulation of Glucosylceramide in Murine Testis, Caused by Inhibition of β-Glucosidase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

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Selective construction of carbocyclic eight-membered rings by ring-closing metathesis of acyclic precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

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Amphiphilic 1-Deoxynojirimycin Derivatives through Click Strategies for Chemical Chaperoning in N370S Gaucher Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From Carbohydrates to Polyoxygenated Cyclooctenes via Ring-Closing Metathesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

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Efficient and Facile Glycol Cleavage Oxidation Using Improved Silica Gel-Supported Sodium Metaperiodate

1 reference

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Disparities in rates of unintended pregnancy in the United States, 1994 and 2001

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

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Identifiers

10.1021/JO202054G

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

ResearchGate publication ID

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