(Q42322397)

English

Synthesis and evaluation of eight- and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase 2, and other glycosidases

scientific article published on 20 March 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

26 October 2017

Synthesis and evaluation of eight- and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase 2, and other glycosidases (English)

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

1 reference

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inferred from title

9

object named as

Gunda I Georg

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Europe PubMed Central

PMC publication ID

26 October 2017

author name string

Jae Chul Lee

1

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Subhashree Francis

2

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Dinah Dutta

3

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Vijayalaxmi Gupta

4

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Yan Yang

5

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Jin-Yi Zhu

6

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Joseph S Tash

7

1 reference

Europe PubMed Central

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26 October 2017

Ernst Schönbrunn

8

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Europe PubMed Central

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26 October 2017

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publication date

20 March 2012

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Europe PubMed Central

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26 October 2017

Journal of Organic Chemistry

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Europe PubMed Central

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26 October 2017

77

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Europe PubMed Central

PMC publication ID

26 October 2017

7

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

3082-3098

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Identification of potent and selective glucosylceramide synthase inhibitors from a library of N-alkylated iminosugars

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Binding of 3,4,5,6-Tetrahydroxyazepanes to the Acid-β-glucosidase Active Site: Implications for Pharmacological Chaperone Design for Gaucher Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Iminosugars as therapeutic agents: recent advances and promising trends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Oral administration of a retinoic Acid receptor antagonist reversibly inhibits spermatogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Therapeutic applications of iminosugars: current perspectives and future opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Methylthioinosine Phosphorylase from Pseudomonas aeruginosa . Structure and Annotation of a Novel Enzyme in Quorum Sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Recent methodological advances in male hormonal contraception

1 reference

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26 October 2017

Iminosugars past, present and future: medicines for tomorrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Hormonal approaches to male contraception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Abortion in the United States: incidence and access to services, 2005.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

New perspectives in non-hormonal male contraception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat Sertoli cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Oral maintenance clinical trial with miglustat for type I Gaucher disease: switch from or combination with intravenous enzyme replacement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

C-Alkyl 5-membered ring imino sugars as new potent cytotoxic glucosylceramide synthase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Pharmacological enhancement of mutated alpha-glucosidase activity in fibroblasts from patients with Pompe disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Miglustat has no apparent effect on spermatogenesis in normal men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Disparities in Rates of Unintended Pregnancy In the United States, 1994 and 2001

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Therapeutic applications of imino sugars in lysosomal storage disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Low dose gossypol for male contraception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Antifertility Actions of a-Chlorohydrin in the Male

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

26 October 2017

Biochemical and structural study on a S529V mutant acid α-glucosidase responsive to pharmacological chaperones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Molecular interaction of imino sugars with human alpha-galactosidase: Insight into the mechanism of complex formation and pharmacological chaperone action in Fabry disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

From D-glucose to enantiomerically pure cycloctanoses. The glycosidase inhibitory capacity of medium-ring carbasugars.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Biological properties of D- and L-1-deoxyazasugars

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Surprising bacterial nucleotidyltransferase selectivity in the conversion of carbaglucose-1-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Low-dose N-butyldeoxynojirimycin (OGT 918) for type I Gaucher disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

17 August 2018

Advances in male contraception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431965

30 September 2018

Convergent approach toward the synthesis of the stereoisomers of C-6 homologues of 1-deoxynojirimycin and their analogues: evaluation as specific glycosidase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

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inferred from PubMed ID database lookup

Inhibition of Glycosphingolipid Biosynthesis: Application to Lysosomal Storage Disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of (+)-mycalamide A

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the constituents of Broussonetia species. VII. Four new pyrrolidine alkaloids, broussonetines M, O, P, and Q, as inhibitors of glycosidase, from Broussonetia kazinoki SIEB

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of adamantan-1-yl-methoxy-functionalized 1-deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

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inferred from PubMed ID database lookup

Inhibition of nonmammalian glycosidases by azetidine iminosugars derived from stable 3,5-di-O-triflates of pentoses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of Glucosylceramide in Murine Testis, Caused by Inhibition of β-Glucosidase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective construction of carbocyclic eight-membered rings by ring-closing metathesis of acyclic precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiphilic 1-Deoxynojirimycin Derivatives through Click Strategies for Chemical Chaperoning in N370S Gaucher Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From Carbohydrates to Polyoxygenated Cyclooctenes via Ring-Closing Metathesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient and Facile Glycol Cleavage Oxidation Using Improved Silica Gel-Supported Sodium Metaperiodate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disparities in rates of unintended pregnancy in the United States, 1994 and 2001

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JO202054G

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

ResearchGate publication ID

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