(Q42365884)

English

Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei

scientific article published on 5 November 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei (English)

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

1 reference

based on heuristic

inferred from title

Theonella swinhoei

object named as

Theonella swinhoei

1 reference

based on heuristic

inferred from title

Angela Zampella

13

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Simona De Marino

object named as

Simona De Marino

5

0 references

Giuseppe Bifulco

object named as

Giuseppe Bifulco

9

0 references

Orazio Taglialatela-Scafati

4

object named as

Orazio Taglialatela-Scafati

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

7

object named as

Barbara Renga

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

1

object named as

Valentina Sepe

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Maria Valeria D'Auria

3

object named as

Maria Valeria D'Auria

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

author name string

Raffaella Ummarino

2

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Claudio D'Amore

6

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Maria Giovanna Chini

8

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Yoichi Nakao

10

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Nobuhiro Fusetani

11

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Stefano Fiorucci

12

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

5 November 2012

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

10

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

11

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

2448-2466

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

copyright license

Creative Commons Attribution 4.0 International

5 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Marine sponge steroids as nuclear receptor ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Heat shock proteins as key biological targets of the marine natural cyclopeptide perthamide C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Development of FXR, PXR and CAR agonists and antagonists for treatment of liver disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Natural ligands for nuclear receptors: biology and potential therapeutic applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Farnesoid X receptor agonist for the treatment of liver and metabolic disorders: focus on 6-ethyl-CDCA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Nuclear receptors CAR and PXR; therapeutic targets for cholestatic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Solomonsterols A and B from Theonella swinhoei. The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Targeting farnesoid X receptor for liver and metabolic disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Farnesoid X receptor: from structure to potential clinical applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Structural basis for bile acid binding and activation of the nuclear receptor FXR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Python: a programming language for software integration and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

29 May 2018

Quantitative NMR-derived interproton distances combined with quantum mechanical calculations of 13C chemical shifts in the stereochemical determination of conicasterol F, a nuclear receptor ligand from Theonella swinhoei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

17 August 2018

Swinholide J, a potent cytotoxin from the marine sponge Theonella swinhoei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

17 August 2018

Solomonamides A and B, new anti-inflammatory peptides from Theonella swinhoei.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

17 August 2018

Excellent long-term survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic Acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

17 August 2018

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3509528

17 August 2018

Regio- and Stereospecific Synthesis of Cholesterol Derivatives and Their Hormonal Activity inCaenorhabditis elegans

1 reference

https://api.crossref.org/works/10.3390%2FMD10112448

21 January 2018

4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23203270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ten-year survival in ursodeoxycholic acid-treated patients with primary biliary cirrhosis. The UDCA-PBC Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/23203270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MD10112448

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

ResearchGate publication ID

0 references

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