(Q42366758)

28 October 2017

Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1. (English)

1 reference

28 October 2017

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Bernd Simon

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Valentin Wittmann

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Maja Köhn

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Miriam Fontanillo

1

1 reference

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2 June 2020

Ivan Zemskov

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Maximilian Häfner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ulrike Uhrig

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

10 October 2016

1 reference

Angewandte Chemie International Edition

28 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

55

1 reference

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2 June 2020

issue

45

1 reference

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2 June 2020

page(s)

13985-13989

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling

2 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Serine/threonine phosphatases: mechanism through structure

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

From promiscuity to precision: protein phosphatases get a makeover

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase Inhibitors

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Protein phosphatase inhibition: structure based design. Towards new therapeutic agents

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Conformational studies of microcystin-LR using NMR spectroscopy and molecular dynamics calculations

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Comparison of the solution structures of microcystin-LR and motuporin

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Naming of cyclic heptapeptide toxins of cyanobacteria (blue-green algae).

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Formation, characterization, and toxicity of the glutathione and cysteine conjugates of toxic heptapeptide microcystins

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Development of a colorimetric and a fluorescence phosphatase-inhibitor assay suitable for drug discovery approaches.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Computational study of the covalent bonding of microcystins to cysteine residues--a reaction involved in the inhibition of the PPP family of protein phosphatases

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Microcystin analogues comprised only of Adda and a single additional amino acid retain moderate activity as PP1/PP2A inhibitors

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

A colorimetric and fluorometric microplate assay for the detection of microcystin-LR in drinking water without preconcentration

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113787

Enantiospecific synthesis of N-Boc-Adda: a linear approach

17 August 2018

1 reference

12 December 2020

Comparative toxicity of four microcystins of different hydrophobicities to the protozoan, Tetrahymena pyriformis

1 reference

12 December 2020

All-L-Leu-Pro-Leu-Pro: a challenging cyclization

1 reference

12 December 2020

Human and rat hepatocyte toxicity and protein phosphatase 1 and 2A inhibitory activity of naturally occurring desmethyl-microcystins and nodularins

1 reference

12 December 2020

Identifiers

DOI

10.1002/ANIE.201606449

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27723199%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference