(Q42370647)

28 October 2017

1 reference

11 August 2020

Genetic epidemiology and Mendelian randomization for informing disease therapeutics: Conceptual and methodological challenges (English)

1 reference

28 October 2017

1 reference

17 June 2019

1 reference

19 September 2019

Mendelian randomization

1 reference

PubMed

genome-wide association study

19 September 2019

1 reference

11 August 2020

1

1 reference

28 October 2017

3

1 reference

28 October 2017

Kate Tilling

2

1 reference

28 October 2017

language of work or name

1 reference

5 October 2017

1 reference

28 October 2017

1 October 2017

7 references

14 March 2019

19 March 2019

22 March 2019

22 April 2019

17 June 2019

19 September 2019

11 August 2020

8 references

28 October 2017

14 March 2019

19 March 2019

22 March 2019

22 April 2019

17 June 2019

19 September 2019

11 August 2020

13

1 reference

28 October 2017

10

1 reference

28 October 2017

e1006944

1 reference

Creative Commons Attribution 4.0 International

28 October 2017

7 references

14 March 2019

19 March 2019

22 March 2019

22 April 2019

17 June 2019

19 September 2019

on focus list of Wikimedia project

11 August 2020

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

Genetic risk variants as therapeutic targets for Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Quantifying the extent to which index event biases influence large genetic association studies

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Association of Genetic Risk for Schizophrenia With Nonparticipation Over Time in a Population-Based Cohort Study

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Mendelian randomization studies: a review of the approaches used and the quality of reporting

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

A genome-wide association study of body mass index across early life and childhood

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Instrumental variable estimation in a survival context.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Mendelian randomisation applied to drug development in cardiovascular disease: a review.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Type II secretory phospholipase A2 and prognosis in patients with stable coronary heart disease: mendelian randomization study

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Progression of lumbar disc degeneration over a decade: a heritability study

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

The HapMap and genome-wide association studies in diagnosis and therapy

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Role of Folate in Colon Cancer Development and Progression

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

The human genome project and its impact on psychiatry

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Multiple sclerosis in sibling pairs: an analysis of 250 families

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Remnant cholesterol, low-density lipoprotein cholesterol, and blood pressure as mediators from obesity to ischemic heart disease.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studies.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Causal associations of tobacco smoking with cardiovascular risk factors: a Mendelian randomization analysis of the HUNT Study in Norway.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5628782

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1006944

When Will Mendelian Randomization Become Relevant for Clinical Practice and Public Health?

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1006944

C-Reactive Protein and the Risk of Cancer: A Mendelian Randomization Study

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28981501

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Collider scope: when selection bias can substantially influence observed associations.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28981501

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1006944

1 reference

28 October 2017

1 reference

28 October 2017

PubMed publication ID

28981501

1 reference