(Q42395440)

English

The fraction of activated N-methyl-D-aspartate receptors during synaptic transmission remains constant in the presence of the glutamate release inhibitor riluzole

scientific article published on 21 May 2008

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scholarly article

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493706%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

The fraction of activated N-methyl-D-aspartate receptors during synaptic transmission remains constant in the presence of the glutamate release inhibitor riluzole (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493706%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Christopher G. Parsons

3

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7 January 2020

author name string

G Rammes

1

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7 January 2020

W Zieglgänsberger

2

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7 January 2020

publication date

21 May 2008

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7 January 2020

Journal of Neural Transmission

1 reference

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7 January 2020

115

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7 January 2020

8

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7 January 2020

1119-1126

1 reference

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7 January 2020

https://scigraph.springernature.com/pub.10.1007/s00702-008-0059-y

0 references

Pharmacodynamics of memantine: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Potential role of N-methyl-D-aspartate receptors as executors of neurodegeneration resulting from diverse insults: focus on memantine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Excitotoxicity and amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Neuroprotective agents for clinical trials in ALS: a systematic assessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Amyotrophic lateral sclerosis (motor neuron disease): proposed mechanisms and pathways to treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Diverse mechanisms of antiepileptic drugs in the development pipeline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Pharmacologic approaches to the treatment of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Advances in clinical trials for amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Glutamate in CNS disorders as a target for drug development: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Current pharmacological management of amyotrophic [corrected] lateral sclerosis and a role for rational polypharmacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Riluzole enhances glutamate uptake in rat astrocyte cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Neuroprotective potential of ionotropic glutamate receptor antagonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Selective inhibition by riluzole of voltage-dependent sodium channels and catecholamine secretion in adrenal chromaffin cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Glutamate, excitotoxicity and amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

The pharmacology and mechanism of action of riluzole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Amyotrophic lateral sclerosis: the involvement of intracellular Ca2+ and protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Riluzole anesthesia: use-dependent block of presynaptic glutamate fibers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Inhibition by riluzole of glycinergic postsynaptic currents in rat hypoglossal motoneurones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Activation and desensitization of glutamate-activated channels mediating fast excitatory synaptic currents in the visual cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

28 May 2018

Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

16 August 2018

Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

16 August 2018

Multinational randomised controlled trial of lubeluzole in acute ischaemic stroke. European and Australian Lubeluzole Ischaemic Stroke Study Group.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

16 August 2018

Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

16 August 2018

Neuroprotection of acetylcholinergic basal forebrain neurons by memantine and neurokinin B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

16 August 2018

Riluzole, a novel antiglutamate, blocks GABA uptake by striatal synaptosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516544

16 August 2018

Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lamotrigine-antiparkinsonian activity by blockade of glutamate release?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deactivation and desensitization of non-NMDA receptors in patches and the time course of EPSCs in rat cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, double-blind, placebo-controlled ascending dose tolerance study of 619C89 in acute stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic potentiation of dual-component excitatory postsynaptic currents in the rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective depression of low-release probability excitatory synapses by sodium channel blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00702-008-0059-Y

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7 January 2020

Dimensions Publication ID

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7 January 2020

1 reference

Europe PubMed Central

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7 January 2020

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