(Q42407153)

English

Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

scientific article published on 12 October 2010

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scholarly article

1 reference

Europe PubMed Central

29 October 2017

Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease (English)

1 reference

Europe PubMed Central

29 October 2017

Alzheimer's disease

0 references

0 references

4

1 reference

Europe PubMed Central

29 October 2017

author name string

Zuzana Stozicka

1

1 reference

Europe PubMed Central

29 October 2017

Norbert Zilka

2

1 reference

Europe PubMed Central

29 October 2017

Petr Novak

3

1 reference

Europe PubMed Central

29 October 2017

Ondrej Bugos

5

1 reference

Europe PubMed Central

29 October 2017

Michal Novak

6

1 reference

Europe PubMed Central

29 October 2017

publication date

12 October 2010

1 reference

Europe PubMed Central

29 October 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

29 October 2017

7

1 reference

Europe PubMed Central

29 October 2017

64

1 reference

Europe PubMed Central

29 October 2017

https://scigraph.springernature.com/pub.10.1186/1742-2094-7-64

0 references

Inflammation in neurodegenerative disorders: friend or foe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Use of genetic variation as biomarkers for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Gain in brain immunity in the oldest-old differentiates cognitively normal from demented individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Risk and protective factors for sporadic Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Phagocytosis of amyloid-beta and inflammation: two faces of innate immunity in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Interaction between genes and environment in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Genetic and environmental modifiers of Alzheimer's disease phenotypes in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Impaired regulation of immune responses in cognitive decline and Alzheimer's disease: lessons from genetic association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Discoveries of tau, abnormally hyperphosphorylated tau and others of neurofibrillary degeneration: a personal historical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Genetic dissection of neurodegeneration and CNS inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

The generation and characterization of potentially therapeutic Abeta antibodies in mice: differences according to strain and immunization protocol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Adhesion molecules on normotensive and hypertensive rat brain endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Truncated tau protein as a new marker for Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Glial cytokines in Alzheimer's disease: review and pathogenic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Silver staining of Alzheimer's neurofibrillary changes by means of physical development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Neuropathological stageing of Alzheimer-related changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Increased S100 beta neurotrophic activity in Alzheimer's disease temporal lobe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

28 May 2018

Cytokine polymorphisms and Alzheimer disease: possible associations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Inflammatory reaction versus endogenous peroxisome proliferator-activated receptors expression, re-exploring secondary organ complications of spontaneously hypertensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

NeuroScale, the battery of behavioral tests with novel scoring system for phenotyping of transgenic rat model of tauopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Truncated tau expression levels determine life span of a rat model of tauopathy without causing neuronal loss or correlating with terminal neurofibrillary tangle load.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Effects of the genetic background on cognitive performances of TG2576 mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Neurodegeneration caused by expression of human truncated tau leads to progressive neurobehavioural impairment in transgenic rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Genetic risk profiles for Alzheimer's disease: integration of APOE genotype and variants that up-regulate inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Inflammation of different tissues in spontaneously hypertensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Mapping genetic modulators of amyloid plaque deposition in TgCRND8 transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Differences in the immune response to long term Abeta vaccination in C57BL/6 and B6D2F1 mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Effect of AT1 receptor antagonism on vascular and circulating inflammatory mediators in SHR: role of NF-kappaB/IkappaB system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Identification of loci determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Angiotensin II AT1 receptor blockade reverses pathological hypertrophy and inflammation in brain microvessels of spontaneously hypertensive rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Genetic background regulates -amyloid precursor protein processing and -amyloid deposition in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

The hippocampus in spontaneously hypertensive rats: an animal model of vascular dementia?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Resistance to endotoxin shock in spontaneously hypertensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

S100 beta expression in Alzheimer's disease: relation to neuropathology in brain regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

S100 beta protein expression in Alzheimer disease: potential role in the pathogenesis of neuritic plaques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958906

16 August 2018

Transgenic mouse models of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phagocytosis of neuronal or glial debris by microglial cells: upregulation of MHC class II expression and multinuclear giant cell formation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Genetic Background of Hypertensive, Septic Rats Determines Outcome Improvement With Antibiotic and G-CSF Prophylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocyte adhesion to cerebromicrovascular endothelial cells derived from hypertensive and normotensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-7-64

1 reference

Europe PubMed Central

29 October 2017

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1742-2094-7-64

1 reference

Europe PubMed Central

29 October 2017

1 reference

Europe PubMed Central

29 October 2017

ResearchGate publication ID

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