(Q42444777)

English

The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells

scientific article published on 15 July 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

1 reference

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inferred from title

3

object named as

Derek LeRoith

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

author name string

Joëlle Dupont

1

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Michael Karas

2

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

language of work or name

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publication date

15 July 2003

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

31 October 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

39

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

37256-37264

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Function of the IGF-I receptor in breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Role of IRS-2 in insulin and cytokine signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Characterization of insulin receptor substrate 4 in human embryonic kidney 293 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

G1 phase progression: cycling on cue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

The INK4 family of cell cycle inhibitors in cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Cancer dormancy and cell signaling: induction of p21(waf1) initiated by membrane IgM engagement increases survival of B lymphoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Epidermal growth factor increases the level of the cyclin-dependent kinase (CDK) inhibitor p21/CIP1 (CDK-interacting protein 1) in A431 cells by increasing the half-lives of the p21/CIP1 transcript and the p21/CIP1 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

FGF signaling activates STAT1 and p21 and inhibits the estrogen response and proliferation of MCF-7 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

The cyclin-dependent kinase inhibitor p21WAF1/Cip1 is an antiestrogen-regulated inhibitor of Cdk4 in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

The Raf-1/MEK/ERK pathway regulates the expression of the p21(Cip1/Waf1) gene in chondrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Phosphatidylinositol 3-kinase inhibitors, Wortmannin or LY294002, inhibited accumulation of p21 protein after gamma-irradiation by stabilization of the protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

New functional activities for the p21 family of CDK inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

p21(Waf1/Cip1) is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Inhibitory effect of p21 in MCF-7 cells is overcome by its coordinated stabilization with D-type cyclins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

A positive effect of p21cip1/waf1 in the colony formation from murine myeloid progenitor cells as assessed by retroviral-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

The potentiation of estrogen on insulin-like growth factor I action in MCF-7 human breast cancer cells includes cell cycle components

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Insulin Receptor Substrate-1 is the Predominant Signaling Molecule Activated by Insulin-like Growth Factor-I, Insulin, and Interleukin-4 in Estrogen Receptor-positive Human Breast Cancer Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Expression of insulin-like growth factor-1 receptor (IGF-1R) and p27Kip1 in melanocytic tumors: a potential regulatory role of IGF-1 pathway in distribution of p27Kip1 between different cyclins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Aberrant p21(CIP1/WAF1) protein accumulation in head-and-neck cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302355200

21 January 2018

Identifiers

10.1074/JBC.M302355200

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

ResearchGate publication ID

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