(Q42445249)

English

First assessment in humans of the safety, tolerability, pharmacokinetics, and ex vivo pharmacodynamic antimalarial activity of the new artemisinin derivative artemisone

scientific article published on 16 June 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

First assessment in humans of the safety, tolerability, pharmacokinetics, and ex vivo pharmacodynamic antimalarial activity of the new artemisinin derivative artemisone (English)

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

0 references

0 references

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

Richard K Haynes

object named as

Richard K Haynes

6

0 references

Michael D. Edstein

9

object named as

Michael D Edstein

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

author name string

Johannes Nagelschmitz

1

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Barbara Voith

2

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Georg Wensing

3

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Axel Roemer

4

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Burkhard Fugmann

5

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Barbara M Kotecka

7

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Karl H Rieckmann

8

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

language of work or name

0 references

publication date

16 June 2008

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

52

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

3085-3091

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Population pharmacokinetic assessment of a new regimen of mefloquine used in combination treatment of uncomplicated falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Artemisinin-based combinations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Antimalarial drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Developing artemisinin based drug combinations for the treatment of drug resistant falciparum malaria: A review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

The assessment of antimalarial drug efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Artemisinin pharmacokinetics and efficacy in uncomplicated-malaria patients treated with two different dosage regimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Artemisinin drugs: novel antimalarial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

In vitro neurotoxicity of artemisinin derivatives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Assessment of the neurotoxicity of parenteral artemisinin derivatives in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Pharmacokinetics and ex vivo anti-malarial activity of sera following a single oral dose of dihydroartemisinin in healthy Thai males

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Assessment of the pharmacodynamic properties of antimalarial drugs in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Single dose pharmacokinetics of oral artemether in healthy Malaysian volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Artemisinin neurotoxicity: neuropathology in rats and mechanistic studies in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Chloroquine bioassay of plasma specimens obtained from soldiers on chloroquine plus doxycycline for malaria prophylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Comparative bioavailability of oral, rectal, and intramuscular artemether in healthy subjects: use of simultaneous measurement by high performance liquid chromatography and bioassay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Multiple dose pharmacokinetics of oral artemisinin and comparison of its efficacy with that of oral artesunate in falciparum malaria patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Artemisinin: current status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Neurotoxicity of artemisinin analogs in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

The pharmacokinetics of a single dose of artemisinin in healthy Vietnamese subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Resistance of ten Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Clinical trial of artesunate and artemether on multidrug resistant falciparum malaria in Thailand. A preliminary report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

28 May 2018

Artemisone--a highly active antimalarial drug of the artemisinin class

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

16 August 2018

The pharmacokinetics of oral dihydroartemisinin and artesunate in healthy Thai volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

16 August 2018

Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

16 August 2018

Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

16 August 2018

Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533467

16 August 2018

Fatal neurotoxicity of arteether and artemether

1 reference

https://pubmed.ncbi.nlm.nih.gov/18559649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The toxicity of artemisinin and related compounds on neuronal and glial cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/18559649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/18559649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.01585-07

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

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