(Q42446615)

31 October 2017

title

Site-directed mutagenesis of the ATM promoter: consequences for response to proliferation and ionizing radiation (English)

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31 October 2017

Nuri Gueven

1

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31 October 2017

Karen Keating

2

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31 October 2017

Toshiyuki Fukao

3

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31 October 2017

Heidi Loeffler

4

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31 October 2017

Naomi Kondo

5

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31 October 2017

H Peter Rodemann

6

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31 October 2017

Martin F Lavin

7

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31 October 2017

publication date

1 October 2003

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Genes, Chromosomes and Cancer

31 October 2017

published in

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31 October 2017

volume

38

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31 October 2017

issue

2

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31 October 2017

page(s)

157-167

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

31 October 2017

cites work

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7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

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7 January 2021

NF-kappaB and AP-1 are responsible for inducibility of the IL-6 promoter by ionizing radiation in HeLa cells

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7 January 2021

ATM is a target for positive regulation by E2F-1.

1 reference

7 January 2021

Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription

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7 January 2021

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

1 reference

7 January 2021

A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies

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7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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7 January 2021

New mutations, polymorphisms, and rare variants in the ATM gene detected by a novel SSCP strategy

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7 January 2021

CAND3: A ubiquitously expressed gene immediately adjacent and in opposite transcriptional orientation to the ATM gene at 1lq23.1.

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7 January 2021

Upregulation of ATM in sclerosing adenosis of the breast

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7 January 2021

On the nature of a defect in cells from individuals with ataxia-telangiectasia

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7 January 2021

Rapid radiation-induction of ATM protein levels in situ

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7 January 2021

Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

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7 January 2021

AP-1, CREB and CBP transcription factors differentially regulate the tyrosine hydroxylase gene

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7 January 2021

Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos

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7 January 2021

Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia.

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7 January 2021

Ionizing radiation activates c-Jun NH2-terminal kinase (JNK/SAPK) via a PKC-dependent pathway in human thyroid cells

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7 January 2021

X-irradiation induces up-regulation of ATM gene expression in wild-type lymphoblastoid cell lines, but not in their heterozygous or homozygous ataxia-telangiectasia counterparts

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7 January 2021

Identification and characterization of a new gene physically linked to the ATM gene

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7 January 2021

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

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7 January 2021

Identification of target genes for EWS/ATF-1 chimeric transcription factor.

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7 January 2021

Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein.

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7 January 2021

ATM associates with and phosphorylates p53: mapping the region of interaction

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7 January 2021

Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line

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7 January 2021

ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation

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7 January 2021

The genetic defect in ataxia-telangiectasia

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7 January 2021

Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts

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7 January 2021

Development of synthetic promoters for radiation-mediated gene therapy

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7 January 2021

Radiation-induced transcription factor activation in the rat cerebral cortex

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7 January 2021

Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer

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7 January 2021

c-IAP2 is induced by ionizing radiation through NF-kappaB binding sites

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7 January 2021

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

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7 January 2021

Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains

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7 January 2021

Signal transduction and the Ets family of transcription factors

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7 January 2021

Identifiers

DOI

10.1002/GCC.10261

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31 October 2017

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