(Q42447413)

English

Identification of two different states of P-glycoprotein in its catalytic cycle: role of the linker region in the transition between these two states

scientific article published on 10 September 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 October 2017

Identification of two different states of P-glycoprotein in its catalytic cycle: role of the linker region in the transition between these two states (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

author name string

U Subrahmanyeswara Rao

1

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Shanthy L Nuti

2

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

language of work or name

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publication date

10 September 2003

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Europe PubMed Central

PubMed publication ID

31 October 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

31 October 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

47

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

46576-46582

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Isolation and expression of a complementary DNA that confers multidrug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Photoaffinity labels for characterizing drug interaction sites of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Both ATP sites of human P-glycoprotein are essential but not symmetric

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Activation of the human P-glycoprotein ATPase by trypsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Proteolytic Cleavage of the Linker Region of the Human P-glycoprotein Modulates Its ATPase Function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Activation of large conductance sodium channels upon expression of amiloride-sensitive sodium channel in Sf9 insect cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Drug binding and nucleotide hydrolyzability are essential requirements in the vanadate-induced inhibition of the human P-glycoprotein ATPase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

The catalytic cycle of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Phospholipid phase transitions in model and biological membranes as studied by infrared spectroscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308078200

21 January 2018

Identifiers

10.1074/JBC.M308078200

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

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