(Q42464125)

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Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats

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Europe PubMed Central

PubMed publication ID

1 November 2017

Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats (English)

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Europe PubMed Central

PubMed publication ID

1 November 2017

phosphorylation

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Adria Giacca

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Europe PubMed Central

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1 November 2017

author name string

Michael A Király

1

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Europe PubMed Central

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1 November 2017

Jon Campbell

2

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1 November 2017

Edward Park

3

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1 November 2017

Holly E Bates

4

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Europe PubMed Central

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1 November 2017

Jessica T Y Yue

5

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1 November 2017

Venket Rao

6

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1 November 2017

Stephen G Matthews

7

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1 November 2017

George Bikopoulos

8

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Europe PubMed Central

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1 November 2017

Maria Rozakis-Adcock

9

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1 November 2017

Mladen Vranic

11

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1 November 2017

Michael C Riddell

12

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1 November 2017

publication date

8 December 2009

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1 November 2017

American Journal of Physiology - Endocrinology and Metabolism

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1 November 2017

298

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1 November 2017

3

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1 November 2017

E671-82

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Europe PubMed Central

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1 November 2017

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

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21 January 2018

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

1 reference

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21 January 2018

IKK-beta links inflammation to obesity-induced insulin resistance

1 reference

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21 January 2018

Control of gluconeogenic genes during intense/prolonged exercise: hormone-independent effect of muscle-derived IL-6 on hepatic tissue and PEPCK mRNA.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Recurrent intermittent restraint delays fed and fasting hyperglycemia and improves glucose return to baseline levels during glucose tolerance tests in the Zucker diabetic fatty rat--role of food intake and corticosterone.

1 reference

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21 January 2018

Adaptation to mild, intermittent stress delays development of hyperglycemia in the Zucker diabetic Fatty rat independent of food intake: role of habituation of the hypothalamic-pituitary-adrenal axis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Bradykinin augments insulin-stimulated glucose transport in rat adipocytes via endothelial nitric oxide synthase-mediated inhibition of Jun NH2-terminal kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

The effect of physical training on insulin production in obesity

1 reference

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21 January 2018

Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver

1 reference

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21 January 2018

Biochemistry and molecular cell biology of diabetic complications

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21 January 2018

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

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21 January 2018

Voluntary wheel running initially increases adrenal sensitivity to adrenocorticotrophic hormone, which is attenuated with long-term training

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Merit of physical exercise to reverse the higher gene expression of hepatic phosphoenolpyruvate carboxykinase in obese Zucker rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Exercise training improves muscle insulin resistance but not insulin receptor signaling in obese Zucker rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study

1 reference

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21 January 2018

Prevention of hyperglycemia in Zucker diabetic fatty rats by exercise training: effects on gene expression in insulin-sensitive tissues determined by high-density oligonucleotide microarray analysis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Acute stress suppresses pro-inflammatory cytokines TNF-alpha and IL-1 beta independent of a catecholamine-driven increase in IL-10 production

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Serum Resistin (FIZZ3) Protein Is Increased in Obese Humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Exercise training reverses insulin resistance in muscle by enhanced recruitment of GLUT-4 to the cell surface.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Muscle-derived interleukin-6: mechanisms for activation and possible biological roles

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Effect of voluntary wheel running on circadian corticosterone release and on HPA axis responsiveness to restraint stress in Sprague-Dawley rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Exercise training increases glucose transporter protein GLUT-4 in skeletal muscle of obese Zucker (fa/fa) rats.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Increased oxidative stress in obesity and its impact on metabolic syndrome

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Markers of experimental acute inflammation in the Wistar Han rat with particular reference to haptoglobin and C-reactive protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Physical exercise enhances hepatic insulin signaling and inhibits phosphoenolpyruvate carboxykinase activity in diabetes-prone Psammomys obesus

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

A central role for JNK in obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

1 reference

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21 January 2018

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

1 reference

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21 January 2018

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Environmental stress modifies glycemic control and diabetes onset in type 2 diabetes prone Otsuka Long Evans Tokushima Fatty (OLETF) rats.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Fuel selection in human skeletal muscle in insulin resistance: a reexamination

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

1 reference

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21 January 2018

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

1 reference

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Swim training prevents hyperglycemia in ZDF rats: mechanisms involved in the partial maintenance of beta-cell function

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21 January 2018

Attenuation of type 2 diabetes mellitus in the male Zucker diabetic fatty rat: the effects of stress and non-volitional exercise

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Interleukin-6 depletion selectively improves hepatic insulin action in obesity

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-delta

1 reference

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21 January 2018

How obesity causes diabetes: not a tall tale

1 reference

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21 January 2018

c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Modulation of the JNK pathway in liver affects insulin resistance status

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

The anti-inflammatory effect of exercise

1 reference

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21 January 2018

Long-term AICAR administration and exercise prevents diabetes in ZDF rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

The role of TNF alpha in adipocyte metabolism.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

PKC-delta-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Increased glucose uptake promotes oxidative stress and PKC-delta activation in adipocytes of obese, insulin-resistant mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Inflammation, stress, and diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

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Enhancement of muscle glucose uptake by the vasopeptidase inhibitor, omapatrilat, is independent of insulin signaling and the AMP kinase pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90575.2008

21 January 2018

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

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Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

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Global and societal implications of the diabetes epidemic

1 reference

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Identifiers

10.1152/AJPENDO.90575.2008

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

ResearchGate publication ID

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