(Q42471915)

English

Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus.

scientific article published on May 1999

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7 December 2019

Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus (English)

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7 December 2019

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Mus musculus

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Richard J Smeyne

5

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7 December 2019

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K Hamre

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7 December 2019

R Tharp

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7 December 2019

K Poon

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7 December 2019

X Xiong

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7 December 2019

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1 May 1999

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7 December 2019

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7 December 2019

828

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7 December 2019

1-2

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7 December 2019

91-103

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7 December 2019

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MPTP-induced oxidative stress and neurotoxicity are age-dependent: evidence from measures of reactive oxygen species and striatal dopamine levels

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Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

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Sustained depletion of cortical and hippocampal serotonin and norepinephrine but not striatal dopamine by 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH2-MPTP): a comparative study with 2'-CH3-MPTP and MPTP.

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The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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Differential interactive effects of gliotoxin and MPTP in the substantia nigra and the locus coeruleus in BALB/c mice.

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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytes

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7 January 2021

Iron-mediated bioactivation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in glial cultures

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Genetic variability of the CYP 2D6 gene is not a risk factor for sporadic Parkinson's disease

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Estrogen as a neuroprotectant against MPTP-induced neurotoxicity in C57/B1 mice.

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MPTP- and MPP(+)-induced effects on body temperature exhibit age- and strain-dependence in mice

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7 January 2021

The dopamine-depleting effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in CD-1 mice are gender-dependent.

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7 January 2021

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

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7 January 2021

A susceptibility locus for Parkinson's disease maps to chromosome 2p13.

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7 January 2021

The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse

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7 January 2021

Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease

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7 January 2021

Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources.

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Parkinsonism: onset, progression, and mortality

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Interrelationships of loss of vascular competence, ATP depletion, and decreased tissue compressibility in developing myocardial infarcts

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Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the dog: effect of pargyline pretreatment.

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Striatal concentrations of vesicular monoamine transporters are identical in MPTP-sensitive (C57BL/6) and -insensitive (CD-1) mouse strains.

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7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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Pretreatment with nimodipine prevents MPTP-induced neurotoxicity at the nigral, but not at the striatal level in mice

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Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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Genetic influences on nicotine responses

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[3H]harman binding experiments. II: Regional and subcellular distribution of specific [3H]harman binding and monoamine oxidase subtypes A and B activity in marmoset and rat.

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The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method

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Molecular dissection of quantitative traits: progress and prospects

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inferred from DOI database lookup

Identifiers

10.1016/S0006-8993(99)01273-1

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10320728%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10320728%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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