(Q42473618)

1 November 2017

title

Breast cancer cells with inhibition of p38alpha have decreased MMP-9 activity and exhibit decreased bone metastasis in mice (English)

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1 November 2017

2

Melinda A Merrell

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1 November 2017

author name string

Catalina Suarez-Cuervo

1

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1 November 2017

Latania Watson

3

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1 November 2017

Kevin W Harris

4

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1 November 2017

Eben L Rosenthal

5

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1 November 2017

H Kalervo Väänänen

6

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1 November 2017

Katri S Selander

7

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1 November 2017

publication date

1 January 2004

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Clinical & Experimental Metastasis

1 November 2017

published in

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1 November 2017

volume

21

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1 November 2017

issue

6

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1 November 2017

page(s)

525-533

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https://scigraph.springernature.com/pub.10.1007/s10585-004-3503-x

1 November 2017

exact match

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cites work

Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling

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12 December 2020

Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells

1 reference

12 December 2020

Relationship of bone destruction in skeletal metastases to osteoclast activation and prostaglandins

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12 December 2020

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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12 December 2020

p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells

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12 December 2020

Skeletal complications of malignancy

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12 December 2020

Transforming growth factor beta1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells

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12 December 2020

Transcriptional activation of collagenase-3 by transforming growth factor-beta1 is via MAPK and Smad pathways in human breast cancer cells.

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12 December 2020

Inhibition of fibroblast-induced angiogenic phenotype of cultured endothelial cells by the overexpression of tissue inhibitor of metalloproteinase (TIMP)-3.

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12 December 2020

Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis

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12 December 2020

Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38alpha mitogen-activated protein kinase activity

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12 December 2020

Dissemination and growth of cancer cells in metastatic sites

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12 December 2020

Regulation by p38 mitogen-activated protein kinase of adenylate- and uridylate-rich element-mediated urokinase-type plasminogen activator (uPA) messenger RNA stability and uPA-dependent in vitro cell invasion.

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12 December 2020

TGF beta-1 regulation of VEGF production by breast cancer cells

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12 December 2020

Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients

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12 December 2020

Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways

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12 December 2020

Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity.

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12 December 2020

Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay

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12 December 2020

p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity

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12 December 2020

Mutation rate of MAP2K4/MKK4 in breast carcinoma

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12 December 2020

IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis

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12 December 2020

A multigenic program mediating breast cancer metastasis to bone

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12 December 2020

TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

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12 December 2020

Urokinase plasminogen activator system gene expression is increased in human breast carcinoma and its bone metastases--a comparison of normal breast tissue, non-invasive and invasive carcinoma and osseous metastases

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12 December 2020

Platelet-derived growth factor activates p38 mitogen-activated protein kinase through a Ras-dependent pathway that is important for actin reorganization and cell migration

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12 December 2020

Up-regulation of vascular endothelial growth factor in breast cancer cells by the heregulin-beta1-activated p38 signaling pathway enhances endothelial cell migration.

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12 December 2020

Involvement of chemokine receptors in breast cancer metastasis

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12 December 2020

New functions for the matrix metalloproteinases in cancer progression

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12 December 2020

Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway

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12 December 2020

A murine model of experimental metastasis to bone and bone marrow.

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12 December 2020

Breast cancer-induced angiogenesis: multiple mechanisms and the role of the microenvironment

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12 December 2020

Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation

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12 December 2020

Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.

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12 December 2020

Human breast cancer cells induced angiogenesis, recruitment, and activation of osteoclasts in osteolytic metastasis

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12 December 2020

Mechanisms of osteolytic bone metastases in breast carcinoma

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12 December 2020

Expression of human collagenase-3 (MMP-13) by fetal skin fibroblasts is induced by transforming growth factor beta via p38 mitogen-activated protein kinase

1 reference

12 December 2020

p38MAPK induces cell surface alpha4 integrin downregulation to facilitate erbB-2-mediated invasion

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12 December 2020

Expression of erbB/HER receptors, heregulin and P38 in primary breast cancer using quantitative immunohistochemistry

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12 December 2020

Arterial microvascularization and breast cancer colonization in bone.

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12 December 2020

The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis

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12 December 2020

Alpha(v) integrin, p38 mitogen-activated protein kinase, and urokinase plasminogen activator are functionally linked in invasive breast cancer cells

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12 December 2020

Tumor necrosis factor-alpha induces interleukin-6 production via extracellular-regulated kinase 1 activation in breast cancer cells

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12 December 2020

A matrix metalloproteinase inhibitor, batimastat, retards the development of osteolytic bone metastases by MDA-MB-231 human breast cancer cells in Balb C nu/nu mice

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12 December 2020

The p38 MAPK pathway is required for cell growth inhibition of human breast cancer cells in response to activin

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12 December 2020

Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17

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12 December 2020

The skeleton as a unique environment for breast cancer cells

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12 December 2020

p38 MAP kinases: beyond the stress response

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12 December 2020

Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis

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12 December 2020

Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer

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12 December 2020

10.1007/S10585-004-3503-X

Identifiers

DOI

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Dimensions Publication ID

1 November 2017

1016630879

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Fatcat ID

release_fk4f22w4irf7xlrtgrvw4rgd5m

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Fatcat

https://api.fatcat.wiki/v0/release/fk4f22w4irf7xlrtgrvw4rgd5m

24 November 2022

mapped directly with Wikidata item

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