(Q42480705)

1 November 2017

title

Chemokine receptor antagonists: novel therapeutics for inflammation and AIDS. (English)

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1 November 2017

Ponath PD

1

1 reference

1 November 2017

language of work or name

English

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publication date

1 January 1998

1 reference

Expert Opinion on Investigational Drugs

1 November 2017

published in

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1 November 2017

volume

7

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1 November 2017

issue

1

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1 November 2017

page(s)

1-18

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Properties of the novel proinflammatory supergene "intercrine" cytokine family.

1 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Identification and characterization of an inhibitor of haemopoietic stem cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

gro-beta, a -C-X-C- chemokine, is an angiogenesis inhibitor that suppresses the growth of Lewis lung carcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Requirement of MIP-1 alpha for an inflammatory response to viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Lymphotactin: a cytokine that represents a new class of chemokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

A new class of membrane-bound chemokine with a CX3C motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

The molecular biology of leukocyte chemoattractant receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Chemokine antagonists that discriminate between interleukin-8 receptors. Selective blockers of CXCR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Deletion of the NH2-terminal residue converts monocyte chemotactic protein 1 from an activator of basophil mediator release to an eosinophil chemoattractant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

RANTES and MCP-3 antagonists bind multiple chemokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Molecular cloning and functional expression of a new human CC-chemokine receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Cloning and characterization of a specific receptor for the novel CC chemokine MIP-3alpha from lung dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Identification of CCR8, the receptor for the human CC chemokine I-309

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Identification of three related human GRO genes encoding cytokine functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Cloning, bacterial expression and biological characterization of recombinant human granulocyte chemotactic protein-2 and differential expression of granulocyte chemotactic protein-2 and epithelial cell-derived neutrophil activating peptide-78 mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Human Mig chemokine: biochemical and functional characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.7.1.1

21 January 2018

Identifiers

DOI

10.1517/13543784.7.1.1

1 reference

1 November 2017

1 reference