(Q42482831)

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Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity

scientific article published on February 2000

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scholarly article

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Europe PubMed Central

1 November 2017

Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity (English)

1 reference

Europe PubMed Central

1 November 2017

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author name string

C P Yao

1

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Europe PubMed Central

1 November 2017

J W Allen

2

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Europe PubMed Central

1 November 2017

L A Mutkus

3

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Europe PubMed Central

1 November 2017

S B Xu

4

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Europe PubMed Central

1 November 2017

K H Tan

5

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Europe PubMed Central

1 November 2017

M Aschner

6

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Europe PubMed Central

1 November 2017

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publication date

1 February 2000

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1 November 2017

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Europe PubMed Central

1 November 2017

855

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Europe PubMed Central

1 November 2017

1

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Europe PubMed Central

1 November 2017

32-38

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Europe PubMed Central

1 November 2017

Selective modulation of NMDA responses by reduction and oxidation

1 reference

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7 January 2021

Induction of astrocyte metallothioneins (MTs) by zinc confers resistance against the acute cytotoxic effects of methylmercury on cell swelling, Na+ uptake, and K+ release.

1 reference

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7 January 2021

Astrocyte and neuron coculturing method.

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Metallothioneins in brain--the role in physiology and pathology.

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7 January 2021

Uptake of methylmercury in the rat brain: effects of amino acids

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7 January 2021

Methylmercury uptake in rat primary astrocyte cultures: the role of the neutral amino acid transport system.

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7 January 2021

Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures

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A hypothesis regarding the protective role of metallothioneins against the toxicity of DNA interactive anticancer drugs

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7 January 2021

Differential expression of the metallothionein gene in liver and brain of mice and rats.

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7 January 2021

Metallothionein induction by bismuth in neonatal rat primary astrocyte cultures.

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7 January 2021

Analysis of the effects of overexpression of metallothionein-I in transgenic mice on the reproductive toxicology of cadmium

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7 January 2021

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements

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Metallothionein

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7 January 2021

Metallothionein and glutathione as determinants of cellular retention and extrusion of cadmium and mercury

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7 January 2021

Dissociation of neonatal rat brain by dispase for preparation of primary astrocyte cultures.

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7 January 2021

Modification of methylmercury toxicity and metabolism by selenium and vitamin E: possible mechanisms

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Biotinylation of single cysteine mutants of the glutamate transporter GLT-1 from rat brain reveals its unusual topology.

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Metallothionein

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A physicochemical rationale for the biological activity of mercury and its compounds

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7 January 2021

Characterization of metallothionein-I-transgenic mice

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7 January 2021

Metallothioneins: proteins in search of function

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7 January 2021

Use of 51Cr cell labelling to distinguish between release of radiolabelled amino acids from primary astrocyte cultures being due to efflux or cell damage

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7 January 2021

Excitatory amino acid-stimulated uptake of 22Na+ in primary astrocyte cultures.

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7 January 2021

Induction of metallothionein mRNA and protein in murine astrocyte cultures

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7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

A simple method for stabilizing protein-sulfhydryl groups during SDS-gel electrophoresis

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7 January 2021

Transgenic mouse blastocysts that overexpress metallothionein-I resist cadmium toxicity in vitro

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7 January 2021

Effects of butyrate homologues on metallothionein induction in rat primary hepatocyte cultures

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7 January 2021

Transgenic mice that overexpress metallothionein-I are protected from cadmium lethality and hepatotoxicity.

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7 January 2021

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium

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7 January 2021

Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse

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7 January 2021

Oxidative damage to nucleic acids in motor neurons containing mercury

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7 January 2021

Differential modulation by sulfhydryl redox agents and glutathione of GABA- and glycine-evoked currents in rat retinal ganglion cells

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7 January 2021

Cloning and expression of a rat brain L-glutamate transporter

1 reference

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7 January 2021

Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity

1 reference

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7 January 2021

Cloned neuronal IK(A) channels reopen during recovery from inactivation

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7 January 2021

A reentrant loop domain in the glutamate carrier EAAT1 participates in substrate binding and translocation

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7 January 2021

Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase

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Heat shock transcription factor activates yeast metallothionein gene expression in response to heat and glucose starvation via distinct signalling pathways

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7 January 2021

3 Toxicological significance of metallothionein

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Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism.

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7 January 2021

Inhibition of regulatory volume decrease in swollen rat primary astrocyte cultures by methylmercury is due to increased amiloride-sensitive Na+ uptake.

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7 January 2021

Transfection and overexpression of metallothionein-I in neonatal rat primary astrocyte cultures and in astrocytoma cells increases their resistance to methylmercury-induced cytotoxicity

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7 January 2021

Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue.

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7 January 2021

Chemical modulation of metallothionein I and III mRNA in mouse brain

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7 January 2021

Identifiers

10.1016/S0006-8993(99)02211-8

1 reference

Europe PubMed Central

1 November 2017

1 reference

Europe PubMed Central

1 November 2017

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