(Q42484145)

English

Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress.

scientific article published on 18 February 2011

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331471%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress (English)

1 reference

Europe PubMed Central

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22 January 2020

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inferred from title

1 reference

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insulin resistance

1 reference

based on heuristic

inferred from title

11

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22 January 2020

3

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22 January 2020

Christopher J. Lelliott

5

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22 January 2020

author name string

L E Wright

1

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22 January 2020

A E Brandon

2

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22 January 2020

G-B Forsberg

4

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22 January 2020

J Reznick

6

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22 January 2020

L Löfgren

7

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22 January 2020

J Oscarsson

8

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22 January 2020

M Strömstedt

9

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22 January 2020

G J Cooney

10

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22 January 2020

publication date

18 February 2011

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22 January 2020

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22 January 2020

54

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22 January 2020

6

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22 January 2020

1417-1426

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22 January 2020

https://scigraph.springernature.com/pub.10.1007/s00125-011-2068-x

0 references

Disordered lipid metabolism and the pathogenesis of insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Free fatty acids and skeletal muscle insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Is mitochondrial dysfunction a cause of insulin resistance?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

High-fat diets cause insulin resistance despite an increase in muscle mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

1 reference

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21 January 2018

Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Insulin resistance is a cellular antioxidant defense mechanism

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Reactive oxygen species have a causal role in multiple forms of insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

PGC-1 coactivators and skeletal muscle adaptations in health and disease

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Overexpression of peroxisome proliferator-activated receptor gamma coactivator-1alpha down-regulates GLUT4 mRNA in skeletal muscles

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Acute bidirectional manipulation of muscle glucose uptake by in vivo electrotransfer of constructs targeting glucose transporter genes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Hepatic PGC-1beta overexpression induces combined hyperlipidemia and modulates the response to PPARalpha activation.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase -- increased expression with reduced muscle damage

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Retracted: Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Antioxidants prevent health-promoting effects of physical exercise in humans

1 reference

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21 January 2018

Genes involved in mitochondrial biogenesis/function are induced in response to bilio-pancreatic diversion in morbidly obese individuals with normal glucose tolerance but not in type 2 diabetic patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Whole-genome microarray analysis identifies up-regulation of Nr4a nuclear receptors in muscle and liver from diet-restricted rats.

1 reference

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21 January 2018

The effects of apelin treatment on skeletal muscle mitochondrial content

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Reactive oxygen species enhance insulin sensitivity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2068-X

21 January 2018

Elevated Free Fatty Acids Attenuate the Insulin-Induced Suppression of PDK4 Gene Expression in Human Skeletal Muscle: Potential Role of Intramuscular Long-Chain Acyl-Coenzyme A

1 reference

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21 January 2018

Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21331471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21331471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method for the isolation and purification of total lipides from animal tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/21331471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21331471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays of glutathione peroxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21331471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid separation and quantitation of combined neutral and polar lipid classes by high-performance liquid chromatography and evaporative light-scattering mass detection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21331471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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