(Q42484252)

English

Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway.

scientific article published on May 2011

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21338338%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21338338%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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based on heuristic

inferred from title

reactive oxygen species

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based on heuristic

inferred from title

Daniela Valenti

1

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23 January 2020

3

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23 January 2020

Rosa Anna Vacca

5

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23 January 2020

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Gabriella Arcangela Manente

2

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23 January 2020

Ersilia Marra

4

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23 January 2020

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1 May 2011

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23 January 2020

Biochemical Journal

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23 January 2020

435

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23 January 2020

3

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23 January 2020

679-688

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23 January 2020

Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Sequential serum-dependent activation of CREB and NRF-1 leads to enhanced mitochondrial respiration through the induction of cytochrome c.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Contribution of the phosphorylable complex I in the growth phase-dependent respiration of C6 glioma cells in vitro

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

cAMP-dependent protein kinase regulates post-translational processing and expression of complex I subunits in mammalian cells.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Kinase signaling cascades in the mitochondrion: a matter of life or death.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Complex I defect in muscle from patients with Huntington's disease.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Down syndrome--recent progress and future prospects

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Alzheimer disease and Down syndrome: factors in pathogenesis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Mitochondrial dysfunction in mouse trisomy 16 brain

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Mitochondrial production of reactive oxygen species: role of complex I and quinone analogues

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Increased lipid peroxidation in Down's syndrome mouse models.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Accumulation of altered aspartyl residues in erythrocyte proteins from patients with Down's syndrome

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Control of electron flux through the respiratory chain in mitochondria and cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

In the early phase of programmed cell death in Tobacco Bright Yellow 2 cells the mitochondrial adenine nucleotide translocator, adenylate kinase and nucleoside diphosphate kinase are impaired in a reactive oxygen species-dependent manner

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Differential expression of beta 1c integrin messenger ribonucleic acid and protein levels in human endometrium and decidua during the menstrual cycle and pregnancy

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Phosphorylation pattern of the NDUFS4 subunit of complex I of the mammalian respiratory chain

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Control of mitochondria dynamics and oxidative metabolism by cAMP, AKAPs and the proteasome.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Beta-amyloid, oxidative stress and down syndrome

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Generation of superoxide by the mitochondrial Complex I.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

DNA damage and repair in children with Down's syndrome

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101908

21 January 2018

Identifiers

10.1042/BJ20101908

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21338338%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21338338%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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