(Q42486045)

1 November 2017

title

Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators (English)

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1 November 2017

5

Anang Shelat

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1 November 2017

Marie Togashi

3

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Leggy A Arnold

object named as

Leggy A Arnold

1

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R. Kiplin Guy

12

object named as

R Kiplin Guy

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1 November 2017

10

Robert J Fletterick

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1 November 2017

6

Andrea C McReynolds

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1 November 2017

11

Paul Webb

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1 November 2017

Eva Estébanez-Perpiñá

2

object named as

Eva Estébanez-Perpiñá

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1 November 2017

4

Natalia Jouravel

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1 November 2017

7

Ellena Mar

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1 November 2017

Phuong Nguyen

8

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1 November 2017

John D Baxter

9

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1 November 2017

language of work or name

English

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publication date

31 October 2005

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Journal of Biological Chemistry

1 November 2017

published in

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1 November 2017

volume

280

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1 November 2017

issue

52

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1 November 2017

page(s)

43048-43055

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Thyroid hormone ligands and metabolic diseases

1 November 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M506693200

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Cloning and characterization of two novel thyroid hormone receptor beta isoforms

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The nuclear receptor superfamily: the second decade

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Review of the in vivo functions of the p160 steroid receptor coactivator family

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Transcriptional repression by nuclear hormone receptors

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Coregulator interactions with the thyroid hormone receptor.

21 January 2018

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Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

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GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors

21 January 2018

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The TRAP/SMCC/Mediator complex and thyroid hormone receptor function

21 January 2018

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

21 January 2018

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Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator

21 January 2018

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Quantitative proteomics of the thyroid hormone receptor-coregulator interactions

21 January 2018

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CBP and p300: HATs for different occasions

21 January 2018

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Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma

21 January 2018

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A regulatory role for RIP140 in nuclear receptor activation

21 January 2018

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An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

21 January 2018

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Structure and specificity of nuclear receptor-coactivator interactions

21 January 2018

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Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

21 January 2018

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An inhibitor of the interaction of thyroid hormone receptor beta and glucocorticoid interacting protein 1.

21 January 2018

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Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2.

21 January 2018

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Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions

21 January 2018

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Thioether side chain cyclization for helical peptide formation: inhibitors of estrogen receptor-coactivator interactions.

21 January 2018

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Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding

21 January 2018

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Thyroxine analogs. 23. Quantitative structure-activity correlation studies of in vivo and in vitro thyromimetic activities

21 January 2018

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Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1

21 January 2018

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Design of thyroid hormone receptor antagonists from first principles

21 January 2018

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A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor

21 January 2018

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Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine

21 January 2018

1 reference

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Differential effects of triiodothyronine and the thyroid hormone receptor beta-specific agonist GC-1 on thyroid hormone target genes in the b ain.

21 January 2018

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The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity

21 January 2018

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Hormone selectivity in thyroid hormone receptors

21 January 2018

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

21 January 2018

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Modulation of protein-protein interactions with small organic molecules

21 January 2018

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Inhibition of protein-protein association by small molecules: approaches and progress

21 January 2018

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A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization

21 January 2018

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Expression of the rat alpha 1 thyroid hormone receptor ligand binding domain in Escherichia coli and the use of a ligand-induced conformation change as a method for its purification to homogeneity.

21 January 2018

1 reference

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Cytotoxicity of Some Azines of Acetophenone Derived Mono-Mannich Bases against Jurkat Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506693200

Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506693200

21 January 2018

Identifiers

DOI

10.1074/JBC.M506693200

1 reference

1 November 2017

1 reference